Results 131 to 140 of about 780,296 (293)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Errores en geometría: clasificación e incidencia en un curso preuniversitario

open access: yesRevista Iberoamericana de Educación, 2010
Los estudiantes de Ingeniería Agronómica, y también los ingenieros agrónomos, en muchas situaciones diarias, tienen necesidad del reconocimiento de formas, relaciones o estructuras, en definitiva del uso de la geometría.
Mónica Bocco, Claudina Canter
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Analysis of the errors in written composition made by greek cypriot students of spanish as a foreign language (SFL): A1- B1.1 language level [PDF]

open access: yes, 2016
El propósito de este trabajo ha sido investigar los errores morfosintácticos de los alumnos griegochipriotas de español como lengua extranjera en la expresión escrita.
Andreou, Eleftheria   +1 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Manejo de glucómetros: detección de errores e intervención farmacéutica [PDF]

open access: yes, 2010
INTRODUCCIÓN La técnica de automonitorización de la glucemia en sangre capilar (AMG) es una parte esencial en el control de la diabetes y de sus complicaciones.
Beltrán Sanz, Vicente   +7 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Correction to: implementation of second-tier tests in newborn screening for the detection of vitamin B12 related acquired and genetic disorders: results on 258,637 newborns

open access: yesOrphanet Journal of Rare Diseases, 2023
Sonia Pajares   +19 more
doaj   +1 more source

Incertidumbre y efectividad del control con calibres en la industria azucarera

open access: yesRevista Centro Azúcar, 2008
En este trabajo se expresan la relación con los aspectos geométricos y los parámetros estadísticos del control dimensional en los procesos de manufactura, definiendo los errores en el control dimensional con calibres limitadores lisos como error tipo I y
Erenia Cabrera Delgado   +2 more
doaj  

Efecto de la contaminación por lípidos exógenos en la gasometría

open access: yesAdvances in Laboratory Medicine
El objetivo del presente estudio es investigar los efectos de la contaminación de sangre venosa por una solución de lípidos sobre diferentes parámetros, determinados en un moderno analizador de gases en sangre.
Lippi Giuseppe   +6 more
doaj   +1 more source

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