Results 31 to 40 of about 348 (250)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Errores matemáticos y conflictos en la interpretación: Consideraciones para resignificar la enseñanza de las matemáticas

Revista Ciencias Pedagógicas e Innovación
El proceso de enseñanza y aprendizaje de las matemáticas exige docentes con conocimientos sólidos para minimizar errores y facilitar la comprensión estudiantil.
Carlos Iván Bucheli Chaves
doaj   +1 more source

Errores conceptuales institucionalizados en matemáticas

Epistemus, 2014
A raíz de las reflexiones que surgen del análisis del actual Modelo Curricular de la Universidad de Sonora, donde el estudiante ocupa un lugar activo y protagónico en la construcción de su conocimiento y del momento de reflexión y análisis que propicia el inicio de la transición hacia un nuevo modelo curricular basado en Competencias, siendo insistente
Vargas, Ruperto, Parra, María Elena, Díaz, José Luis   +2 more
openaire   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

El problema de las concepciones alternativas en la actualidad (Parte II). El cambio de concepciones alternativas [PDF]

Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2005
En un trabajo anterior (Carrascosa, 2005) analizábamos el problema de las ideas alternativas que afectan a diversos campos de la ciencia y apuntábamos algunas causas que pueden explicar el origen y/o la persistencia de las mismas.
Carrascosa, J.
doaj   +2 more sources

El mapa conceptual y el software CmapTools como herramientas neurodidácticas para la mejora del aprendizaje

Texto Livre: Linguagem e Tecnologia, 2022
Cuando se desarrollan nuevos conceptos en cualquier cambio científico y, por supuesto, en el ámbito de la educación, se genera en muchos casos la idea de que se trata de algo nuevo va a cambiar radicalmente, en nuestro caso, en la forma de educar y ...
José Gijón Puerta, Meriem Khaled Gijón, Ana Matas Lara, Pablo García Sempere   +3 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source