Results 101 to 110 of about 179,010,438 (302)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Topics in the accuracy and resolution of superresolution systems [PDF]
, 2009 Since their introduction in the 1970s and 1980s superresolution systems for point source parameter estimation have received theoretical attention regarding their potential performance.
Brandwood, D.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Over-the-Air Phase Noise Spectral Density Measurement for FMCW Radar Sensors
IEEE Journal of MicrowavesPhase noise significantly degrades the performance of frequency-modulated continuous wave (FMCW)- and chirp sequence (CS)-based radar sensors. Knowledge of the power spectral density (PSD) of these sensors is therefore essential for estimating their ...
Christoph Birkenhauer +2 more
doaj +1 more source
A Pairwise SSD Fingerprinting Method of Smartphone Indoor Localization for Enhanced Usability
Remote Sensing, 2019 Smartphone indoor localization has attracted considerable attention over the past decade because of the considerable business potential in terms of indoor navigation and location-based services.
Fan Yang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
“Signal Corps Intelligence Agency Activities” on Page 18 in the “Quadrennial Report of the Chief Signal Officer, US Army, May 1951-April 1955.” [PDF]
, 1955 This is a brief organizational history of a small special-purpose intelligence agency focused on signal equipment used by foreign armies and on the organization and activities of analogous organizations to the US Army Signal Corps in foreign armies.
Office of the Chief Signal Officer, Department of the Army +1 more
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Errors in Politics: An analysis of the concept of political error
, 2020 Although political errors are likely to be as old as politics itself, it is only in modern times – and I will suggest that it is only with Machiavelli – that the notion of political error clearly emerged on the background of other kinds of errors with ...
Pascal Nouvel, Nouvel, Pascal
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source