Results 121 to 130 of about 177,367 (306)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Indoor Positioning of Visible Light Communication based on Transformer Model

Guangtongxin yanjiu
ObjectiveIn the multipath propagation scenario of indoor visible light communication, Inter-Symbol Interference (ISI) leads to low precision of indoor visible light positioning due to low received signal strength.
YAO Yao, ZHU Yali, SHAO Xinyu
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Improving The Near-Perfect Hybrid Filter Bank Performance In The Presence Of Realization Errors [PDF]

, 2007
Hybrid filter banks have received increasing attention in the literature, for applications such as high-speed, high-resolution A/D and D/A converter design.
Antonio Petraglia, Paulo B. Batalheiro, Marcos Pinheiro Paulo, Mariane R. Petraglia   +3 more
core  

A novel RSSI-based geometric iterative centroid positioningoptimization strategy using commercial Wi-Fi signals

ETRI Journal
The information interaction and positioning technology based on commercialWi-Fi plays a crucial role in expanding the applications for the Internet ofThings and smart homes.
Jin Huang, Xuejie Hu, Yue Tian
doaj   +1 more source

Identification of Abnormal UGW Signals Using Multi-Scale Progressive Reconstruction Network

Acoustics
The use of ultrasonic guided waves (UGWs) is an efficient damage monitoring technique. Due to their characteristics of a wide monitoring range and low power consumption, UGWs have been widely applied in various structural health monitoring fields.
Yangkun Zou, Jiande Wu, Bo Ye, Honggui Cao, Changchun Yang, Yulong Cui   +5 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Feasibility and accuracy of Received Signal Strength-based Multilateration for aircraft localization using crowdsourced data [PDF]

To verify the aircraft position provided by Automatic Dependent Surveillance-Broadcast (ADS-B)transponders, multilateration (MLAT) technique incorporates time difference of arrival (TDOA) measurements at multiple ground-based receivers to estimate the ...
Martjanova, Veronika (author)
core  

Synthetic aperture sonar imaging using compressive sensing and an ultrasound transducer array [PDF]

, 2013
Includes bibliographical references.Compressive sensing (CS) also known as compressive sampling is a technique used to reconstruct or recover the full-length of a signal with only a few non-adaptive measurements.
Jideani, Josiah Chimnanu
core