Results 31 to 40 of about 116,869 (268)
En réponse à un article de J.D. Bengtson
Un certain nombre de comparatistes tentent de relier le basque à d’autres langues dans le cadre de grandes super-familles (phyla) comme le Nostratique ou le Sino- ou Dene-Caucasien. J.D. Bengtson est l’un d’entre-eux. Il y a probablement du vrai dans ce
Michel Morvan
doaj +1 more source
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei +3 more
wiley +1 more source
Remote sensing and ecosystem modeling to simulate terrestrial carbon fluxes
The main goal of this thesis is the establishment of a framework to analyze the forest ecosystems in peninsular Spain in terms of their role in the carbon cycle.
Sergio Sánchez-Ruiz
doaj +1 more source
Diagnosis and Prioritization of Vulnerable Areas of Urban Ecosystem Regulation Services
Rapid urbanization and population growth have led to drastic degradation of urban ecosystem regulation services (ERS). Urgently needed is the identification of vulnerable areas where ERS are being intensively deteriorated, and preparation of measures to ...
Dongwoo Lee, Kyushik Oh, Jungeun Suh
doaj +1 more source
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
IntroductionEndoplasmic reticulum stress (ERS) has sizeable affect on cancer proliferation, metastasis, immunotherapy and chemoradiotherapy resistance.
Shengren Cen +8 more
doaj +1 more source
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li +14 more
wiley +1 more source
Comprehensive Analysis of Endoplasmic Reticulum Stress in Intracranial Aneurysm
BackgroundAberrant endoplasmic reticulum stress (ERS) plays an important role in multiple cardiovascular diseases. However, their implication in intracranial aneurysms (IAs) remains unclear.
Bo Chen +10 more
doaj +1 more source
In evaluating a headache patient, the first task is to identify or exclude secondary headaches based on the history, and the general medical as well as neurological examinations. Physical and neurological examinations are mandatory, overall in emergency room setting. If suspicious features are present, diagnostic testing may also be necessary.
Pietro Cortelli, Marco Aguggia
openaire +4 more sources
Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung
Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu +11 more
wiley +1 more source

