Results 61 to 70 of about 1,872,205 (309)
Advanced Science, EarlyView.In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang +11 more
wiley +1 more source
Advanced Science, EarlyView.This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun +9 more
wiley +1 more source
Global Carbon Fluxes Using Multioutput Gaussian Processes Regression and MODIS Products
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe quantification of carbon fluxes (CFs) is crucial due to their role in the global carbon cycle having a direct impact on Earth's climate. In the last years, considerable efforts have been made to scale CFs from eddy covariance (EC) data to the ...
Manuel Campos-Taberner +6 more
doaj +1 more source
Annual Gross Primary Production from Vegetation Indices: A Theoretically Sound Approach
Remote Sensing, 2017 A linear relationship between the annual gross primary production (GPP) and a PAR-weighted vegetation index is theoretically derived from the Monteith equation.
María Amparo Gilabert +2 more
doaj +1 more source
... Gud er i psyken er i Gud er i psyken er i ...
Psyke & Logos, 2023 Et empirisk materiale bestående af tekst-dele fra et manuskript, som artikel-forfatteren aktuelt har under udarbejdelse, fremlægges i systematiseret og kommenteret form. Manuskriptet som et hele tager udgangspunkt i et begreb: Styrebilleder, som er en betegnelse for forestillings-komplekser, som klient-systemer kan tage til sig og bruge indenfor ...
openaire +1 more source
Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Orthopaedic Surgery, 2020 Objective Endoplasmic reticulum stress (ERS) is present in chondrocytes of osteoarthritis, and the intensity of ERS is related to the degree of cartilage degeneration.
Ke Rong +10 more
doaj +1 more source
Visual processing: Parallel-er and Parallel-er [PDF]
Current Biology, 2001 The mammalian visual system processes many different aspects of the visual scene in separate, parallel channels. Recent experiments suggest that the visual cortex, like the retina, forms parallel circuits even at very fine spatial scales.
openaire +2 more sources
Advanced Science, EarlyView.A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu +5 more
wiley +1 more source
Glycoconjugate secretion in human airways in vitro: effects of epithelium removal
Mediators of Inflammation, 1998 The aim of this study was to examine glycoconjugate secretion in human airways with and without an epithelium. Glycoconjugate release in supernatants derived from human airways in vitro was determined using an ELISA assay with an anti-human mucin ...
H. Sossé-Alaoui +5 more
doaj +1 more source