Results 51 to 60 of about 31,797 (187)

A dissimulate presentation of histoid Hansen's disease in the form of erythema nodosum leprosum

International Journal of Mycobacteriology, 2019
Hansen's disease is a chronic infectious granulomatous disease with varied clinical presentation. Histoid Hansen's disease is an important emerging lepromatous subset of Hansen's disease known to mimic varied dermatoses.
Vikas Pathania, Bhavni Oberoi, Sukriti Baveja, Divya Shelly, Ruby Venugopal, Prerna Shankar   +5 more
doaj   +1 more source

Targeting fibrosis in the treatment of lower urinary tract dysfunction

The Journal of Pathology, Volume 269, Issue 4-5, Page 493-503, August 2026.
Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar, Sophia M Vrba, Emily A Ricke, Zsuzsanna Fabry, Matthew S Lee, Kevin T McVary, William A Ricke   +6 more
wiley   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

MedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma, Qing Wang, Yusheng Zhang, Yang Li, Hongwei Wu, Hongjun Yang, Xianyu Li   +6 more
wiley   +1 more source

Human immunodeficiency virus and leprosy: an update.

, 2011
Coinfection with human immunodeficiency virus (HIV) has a major effect on the natural history of many infectious diseases, particularly mycobacterial diseases.
Lambert, Saba M, Saba M. Lambert, Diana N.J. Lockwood, Lockwood, Diana NJ   +3 more
core   +1 more source

Lepromatous Leprosy With Erythema Nodosum Leprosum

Annals of Internal Medicine: Clinical Cases
Leprosy remains an important mimicker of autoimmune and inflammatory disease, particularly in nonendemic settings. A 30-year-old man from Micronesia presented with synovitis, subcutaneous nodules, and ocular inflammation, with negative rheumatologic ...
Noor Farhoud, Pooja Bhadbhade
doaj   +1 more source

“Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches—A Narrative Review”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Bhaskar Gupta, Manesha Singh, Mohamad Goldust, Kinnor Das, Surajit Gorai, Prajwal Pudasaini, Seema Sitaula, Achyut Pokhrel, Esna Thapa, Sunil Jaiswal   +9 more
wiley   +1 more source

Immunopathogenesis of erythema nodosum leprosum

Intisari Sains Medis, 2021
Leprosy is a chronic granulomatous disease. Its etiology is caused by Mycobacterium leprae (M. leprae). This disease may affect the skin, however it also may affect peripheral nervous system and other organs. The immunologic mechanism of erythema nodosum leprosum (ENL) has not been fully understood.
Made Sanitca Indah, I Gusti Agung Ayu Dwi Karmila   +1 more
openaire   +2 more sources

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

Interventions for erythema nodosum leprosum. A Cochrane review [PDF]

Leprosy Review, 2009
Treatment for erythema nodosum leprosum (ENL), an immunological complication of leprosy, is diverse. We undertook a systematic review as it was not clear which treatments were most beneficial.We did a systematic search to identify randomised controlled trials (RCTs) comparing treatment with placebo, no treatment or another therapy. Two authors assessed
van Veen, NHJ, Lockwood, DNJ, van Brakel, WH, Ramirez, J, Richardus, JH   +4 more
openaire   +3 more sources

Type 2 Lepra Reaction Following Antituberculosis Treatment Initiation in an Elderly Male With Coexisting Hansen's Disease: A Case Report

Respirology Case Reports, Volume 14, Issue 3, March 2026.
We report a case of a man developing erythema nodosum leprosum after initiating treatment for drug‐susceptible pulmonary tuberculosis. This highlights the importance of recognising concomitant leprosy in patients with tuberculosis since these mycobacterial infections require different long‐term multidrug regimens.
Cary Amiel G. Villanueva, Ysabel Regina H. Ortiz, Winlove P. Mojica, Albert B. Albay Jr   +3 more
wiley   +1 more source