Results 61 to 70 of about 31,797 (187)

Livedo reticularis in type 2 lepra reaction: A rare presentation

Indian Dermatology Online Journal, 2014
Type 2 lepra reaction or erythema nodosum leprosum (ENL) is an immune complex syndrome that occurs mostly in lepromatous leprosy and sometimes in borderline lepromatous leprosy patients.
Kikkeri Narayanasetty Naveen, Sharatchandra Bhimrao Athanikar, Spandana Prakash Hegde, Vidisha Sharatchandra Athanikar   +3 more
doaj   +1 more source

Azathioprine in Chronic Recalcitrant Erythema Nodosum Leprosum: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Erythema Nodosum Leprosum (ENL) may have a chronic course which may be recalcitrant to treatment. Preferred treatment modalities are systemic corticosteroids and thalidomide.
Singh Shailendra Vikram Jitendra, Romita Bachaspatimayum, A. Subhalakshmi Devi, S. Rita   +3 more
doaj   +1 more source

Peripheral Neuropathy Associated With Proteasome Inhibitors and Immunomodulatory Drugs: A Pharmacovigilance Disproportionality Analysis Using VigiBase

Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Immunomodulatory drugs (IMIDs) and proteasome inhibitors (PIs) are part of the frontline treatment landscape for multiple myeloma (MM). Despite their effectiveness, these drugs are associated with adverse effects, particularly clinically significant drug‐induced peripheral neuropathy.
Letícia Penna Braga, Cristiane Aparecida Menezes de Pádua, Iwyson Henrique F. da Costa, Paula Lana de Miranda Drummond, Pedro Henrique Carvalho de Souza, Laura Beatriz Fonseca, Marina Alacoque Rodrigues, Jéssica Soares Malta, Adriano Max Moreira Reis   +8 more
wiley   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

ChemMedChem, Volume 20, Issue 18, September 25, 2025.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali, Samet Poyraz, Samet Belveren, Senanur Taş, Mehmet Ali Tamer, Naciye Yaktubay Döndaş, H. Ali Döndaş, Jose Miguel Sansano   +7 more
wiley   +1 more source

Erythema nodosum – review of the literature

, 2016
Erythema nodosum is the most common form of panniculitis. It may have many aetiological factors. Erythema nodosum occurs three to five times more often in female patients.
Piotr Wiland, Aleksandra Starba, Małgorzata Chowaniec   +2 more
core   +1 more source

Beyond Elimination: Unveiling Leprosy Cases in Far West Nepal

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid‐fast bacilli (AFB).
Smriti Lama Thing, Deepak Subedi, Anita Tamang Waiba, Neha Bista, Apsara Hamal, Monika Gurung   +5 more
wiley   +1 more source

Erythema nodosum – presentation of three cases

, 2016
Erythema nodosum (EN) is a well-known form of panniculitis. It may occur as an idiopathic form and also can be induced by certain clinical conditions such as infections and granulomatous diseases such as sarcoidosis.
Piotr Wiland, Aleksandra Starba, Małgorzata Chowaniec   +2 more
core   +1 more source

A Lady with Generalized Nodular Lesions

Journal of Clinical Rheumatology and Immunology
This clinical quiz discusses a condition that can cause generalized nodular lesions, its underlying immunological reactions, and its management.
Ho Tung Wong, Tin Wai Chay, Chi Kit Au, Tin Lok Lai   +3 more
doaj   +1 more source

A retrospective analysis of histopathology of 64 cases of lepra reactions

Indian Journal of Dermatology, 2012
Background: Lepra reactions are not always diagnosable under the microscope. We analyzed skin histopathology in 64 cases of lepra reaction. Aim : To make detailed observations on histopathologic features of type 1 and type 2 lepra reaction (erythema ...
Vijay Adhe, Atul Dongre, Uday Khopkar
doaj   +1 more source