Results 71 to 80 of about 11,797 (185)

Evaluation of the Usefulness of Machine Learning and Artificial Intelligence on Hyperspectral Images in the Diagnosis of Myelodysplastic Syndrome

open access: yesJournal of Biophotonics, Volume 19, Issue 7, July 2026.
Hyperspectral imaging (350–1050 nm) captures spectral information beyond the visible range from bone marrow biopsy specimens. An HSI‐based AI system using machine learning achieved up to 97% accuracy in diagnosing and classifying MDS, outperforming a previous RGB‐based study.
Yasuo Ueda   +6 more
wiley   +1 more source

Advanced fibrosis, TP53 variants and acute/pure erythroid leukaemia: Diagnostic harbingers of ERCC6L2‐related bone marrow failure syndrome?

open access: yes
British Journal of Haematology, EarlyView.
Sai Sudha Valisekka   +3 more
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts

open access: yesHaematologica, 2010
Background During the final stages of differentiation of mammalian erythroid cells, the chromatin is condensed and enucleated. We previously reported that Rac GTPases and their downstream target, mammalian homolog of Drosophila diaphanous 2 (mDia2), are ...
Peng Ji   +4 more
doaj   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, Volume 293, Issue 14, Page 4288-4305, July 2026.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Adult Erythroblastic Sarcoma With PCM1::JAK2 Fusion and a Novel NOP10::NUTM1 Fusion Complicated by Secondary HLH

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT Erythroblastic sarcoma is a rare and aggressive hematologic malignancy presenting as a mass‐forming extramedullary proliferation of immature erythroid cells. Myeloid/lymphoid neoplasms with JAK2 rearrangement, most often PCM1::JAK2, may show eosinophilia, myelofibrosis, and expansion of immature erythroid precursors.
Tong Ge   +6 more
wiley   +1 more source

Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine

open access: yesTransfusion, Volume 66, Issue 7, Page 1257-1264, July 2026.
Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena   +9 more
wiley   +1 more source

Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation

open access: yesScientific Reports, 2017
Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis.
Teruhisa Takagishi   +5 more
doaj   +1 more source

Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications

open access: yes
American Journal of Hematology, Volume 101, Issue 7, Page 1554-1555, July 2026.
Robert T. Means Jr
wiley   +1 more source

Cytotoxic activities of CD8+ T cells collaborate with macrophages to protect against blood-stage murine malaria

open access: yeseLife, 2015
The protective immunity afforded by CD8+ T cells against blood-stage malaria remains controversial because no MHC class I molecules are displayed on parasite-infected human erythrocytes.
Takashi Imai   +6 more
doaj   +1 more source

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