Results 71 to 80 of about 23,516 (234)
Under HEMA conditions, self-replication of human erythroblasts is limited by autophagic death.
, 2011 The number of erythroblasts generated ex-vivo under human-erythroid massive-amplification conditions by mononuclear cells from one unit of adult blood (~10(10)) are insufficient for transfusion (~10(12) red cells), emphasizing the need for studies to ...
Masiello, F +13 more
core +1 more source
Perspectives In Medical Research, 2017 Acute Erythroid Leukemia (AEL) / Acute Myeloid Leukemia M6 (AML M6) is a rare disorder of hematopoietic system and accounts for 1-3% of acute leukemia and 15% of myeloid leukemia. It is characterized by uncontrolled proliferation of erythroblasts and
Pendurthy Anoosha1 , Anandam G2 ,Preethi Soni3
doaj
Bmi-1 Regulates Extensive Erythroid Self-Renewal
Stem Cell Reports, 2015 Red blood cells (RBCs), responsible for oxygen delivery and carbon dioxide exchange, are essential for our well-being. Alternative RBC sources are needed to meet the increased demand for RBC transfusions projected to occur as our population ages.
Ah Ram Kim +9 more
doaj +1 more source
A PHYSIOLOGICAL STUDY OF ERYTHROBLASTS IN THE DUCK [PDF]
Blood, 1947 Abstract 1. A method for the separation of erythroblasts in quantity from normal red cells in the blood of ducks infected with malaria has been described. 2. The erythroblasts in comparison to the normal adult red cells of the duck have a larger cell volume, less hemoglobin, and show a greater discrepancy between the ...
H H, ROSTORFER, R H, RIGDON
openaire +2 more sources
Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency
Haematologica, 2017 Iron plays the central role in oxygen transport by erythrocytes as a constituent of heme and hemoglobin. The importance of iron and heme is also to be found in their regulatory roles during erythroblast maturation.
Masahiro Kobayashi +12 more
doaj +1 more source
Cell Communication and Signaling, 2023 Anemia is the most common manifestation in myelodysplastic syndrome (MDS) patients, but the cause of ineffective hematopoiesis is not fully understood. Enucleation is an important event in the maturation process of erythroblasts. According to a series of
Chao An +5 more
doaj +1 more source
Haematologica, 2016 Ankyrin-R provides a key link between band 3 and the spectrin cytoskeleton that helps to maintain the highly specialized erythrocyte biconcave shape.
T. Satchwell +15 more
semanticscholar +1 more source
Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis
Haematologica, 2019 AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells.
Meriem Ladli +13 more
doaj +1 more source
Calcium Signaling Is Required for Erythroid Enucleation. [PDF]
PLoS ONE, 2016 Although erythroid enucleation, the property of erythroblasts to expel their nucleus, has been known for 7ore than a century, surprisingly little is known regarding the molecular mechanisms governing this unique developmental process.
Christina B Wölwer +3 more
doaj +1 more source
L. donovani infection increases apoptosis of erythroblasts.
, 2013 Apoptosis of bone marrow erythroblasts was examined by flow cytometry from control non-infected hamsters and L. donovani infected hamsters. Apoptosis was determined by Annexin-V binding (A) and the TUNEL Assay (B). Representative flow cytometry plots are
Steve Oghumu (393264) +7 more
core +1 more source