Results 71 to 80 of about 13,873 (221)
, 1968 With the bone marrow of anemic rats, which had received the repeated injections of phenylhydrazine once a day for three to four days, the effects of aminopterin and bromouracil on the nucleic acid metabolism of erythroblasts were observed in vivo ...
Shigehisa, Morio
core +1 more source
British Journal of Haematology, EarlyView.Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov +15 more
wiley +1 more source
Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis
Haematologica, 2019 AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells.
Meriem Ladli +13 more
doaj +1 more source
Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia
European Journal of Haematology, EarlyView.ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco +2 more
wiley +1 more source
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
A PHYSIOLOGICAL STUDY OF ERYTHROBLASTS IN THE DUCK [PDF]
Blood, 1947 Abstract 1. A method for the separation of erythroblasts in quantity from normal red cells in the blood of ducks infected with malaria has been described. 2. The erythroblasts in comparison to the normal adult red cells of the duck have a larger cell volume, less hemoglobin, and show a greater discrepancy between the ...
H H, ROSTORFER, R H, RIGDON
openaire +2 more sources
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini +6 more
wiley +1 more source
F1000Research, 2018 During erythropoiesis, hematopoietic stem and progenitor cells transition to erythroblasts en route to terminal differentiation into enucleated red blood cells.
Kirsten A. Reimer, Karla M. Neugebauer
doaj +1 more source
EIs and erythroblasts phagocytosed by macrophages.
, 2014 (1a) EIs in bone marrow aspirates of patients with IRP (Wright–Giemsa, ×100); (1b) Erythroblasts phagocytosed by macrophages in the bone marrow aspirates of patients with IRP (Wright–Giemsa, ×100).
Shu-Wen Dong (553262) +4 more
core +1 more source
Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine
Transfusion, EarlyView.Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena +9 more
wiley +1 more source