Results 111 to 120 of about 79,234 (272)
ABSTRACT Metabolic disorders are associated with testosterone deficiency, and the cardiometabolic index (CMI) is a recently identified metabolic indicator. The relationship between male biochemical androgen deficiency (MBAD), a precursor to testosterone deficiency, and CMI remains unclear.
Shuai‐Shuai Mao+2 more
wiley +1 more source
Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. [PDF]
In this study, because excessive polycythemia is a predominant trait in some high-altitude dwellers (chronic mountain sickness [CMS] or Monge's disease) but not others living at the same altitude in the Andes, we took advantage of this human experiment ...
Appenzeller, Otto+9 more
core
Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L+8 more
core +1 more source
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij+11 more
wiley +1 more source
The use of genes for performance enhancement: doping or therapy? [PDF]
Recent biotechnological advances have permitted the manipulation of genetic sequences to treat several diseases in a process called gene therapy. However, the advance of gene therapy has opened the door to the possibility of using genetic manipulation ...
Collares, T. F.+4 more
core +4 more sources
Anemia and retinopathy of prematurity: A narrative review
Anemia in infants who are at greatest risk of developing severe retinopathy of prematurity is almost universal. There is plausible evidence in the literature correlating anemia with severe ROP. However, the relationship is complex, and further study is needed to better understand the potential molecular mechanisms for anemia‐associated ROP.
Minali Prasad+3 more
wiley +1 more source
Burn injury has been shown to significantly dampen erythropoiesis in both burn patients and in murine models. Our previous findings elucidated the erythropoietin independent defects in red cell development stages involving erythroid progenitor production
Shirin Hasan+7 more
doaj +1 more source
Migratory behaviour in seasonal environments affects host–pathogen relationships, especially for vector‐transmitted blood parasites of the order Haemosporida. The common starling Sturnus vulgaris is a short‐distance migrant where the north‐eastern European breeding population spend the non‐breeding season in temperate mild western Europe.
Antonija Rimša+5 more
wiley +1 more source
The Neural Crest as the First Production Site of the Erythroid Growth Factor Erythropoietin
While the neural crest is considered the fourth germ layer that originates a variety of tissues during mammalian development, we recently discovered that some neural crest cells and neuroepithelial cells play a unique role in secreting a vital ...
Ikuo Hirano, Norio Suzuki
doaj +1 more source
Purification and Characterization of Recombinant Darbepoetin Alfa from Leishmania tarentolae [PDF]
Darbepoetin alfa is a biopharmaceutical glycoprotein that stimulates erythropoiesis and is used to treat anemia, which associated with renal failure and cancer chemotherapy.
Ansari, J.+8 more
core +1 more source