Results 111 to 120 of about 94,345 (348)

Genocopy of EVI1‐AML with paraneoplastic diabetes insipidus: PRDM16 overexpression by t(1;2)(p36;p21) and enhancer hijacking

British Journal of Haematology, EarlyView.
Summary Diabetes insipidus (DI) in patients with acute myeloid leukaemia (AML) and chromosome 3q alterations (EVI1/PRDM3/MECOM overexpression) constitutes a poorly understood paraneoplasia. A 44‐year‐old patient presented with clinical and morphological features of this syndrome but, surprisingly, disclosed the rare translocation t(1;2)(p36;p21), with ...
Julian List, Etienne Sollier, Fiona Brown‐Burke, Katherine Kelly, Dietmar Pfeifer, Valeria Shlyakhto, Kristina Maas‐Bauer, Milena Pantic, Christoph Plass, Michael Lübbert   +9 more
wiley   +1 more source

Delineation of erythropoietic intermediates by flow cytometry

Frontiers in Hematology
Erythropoiesis occurs through specification from multipotent progenitors to erythroid restricted potential, expansion of erythroid progenitors, and terminal maturation of precursors to red blood cells.
Kathleen E. McGrath
doaj   +1 more source

A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Critical Illness

Frontiers in Medicine, 2019
Burn injury has been shown to significantly dampen erythropoiesis in both burn patients and in murine models. Our previous findings elucidated the erythropoietin independent defects in red cell development stages involving erythroid progenitor production
Shirin Hasan, Shirin Hasan, Maria Camargo Johnson, Maria Camargo Johnson, Ameet R. Kini, Anthony J. Baldea, Kuzhali Muthumalaiappan, Kuzhali Muthumalaiappan   +7 more
doaj   +1 more source

THE RATE OF REMOVAL OF RADIOACTIVE IRON FROM THE PLASMA—AN INDEX OF ERYTHROPOIESIS 1 [PDF]

, 1952
Louis R. Wasserman, Ira A. Rashkoff, Dorothy Leavitt, Joséphine Mayer, S. Port   +4 more
openalex   +1 more source

When, which and how to switch: Navigating JAK inhibitors in myelofibrosis

British Journal of Haematology, EarlyView.
Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan, Imran Omerdeen, Bethan Psaila   +2 more
wiley   +1 more source

Erythropoiesis stimulating agents [PDF]

BMJ, 2007
May not be safe in people with cancer In February 2007, new concerns surfaced over the safety of agents that stimulate erythropoiesis when used to treat anaemia in patients with cancer. These concerns quickly gained the attention of the oncology community and the popular press.
openaire   +2 more sources

Dynamic regulation of erythropoiesis: A computer model of general applicability [PDF]

A mathematical model for the control of erythropoiesis was developed based on the balance between oxygen supply and demand at a renal oxygen detector which controls erythropoietin release and red cell production.
Leonard, J. I.
core   +1 more source

Across species: A comparative perspective on red cell homeostasis and its influence on our understanding of human physiology and disease

British Journal of Haematology, EarlyView.
This review highlights how studies on animal red cells have enriched our understanding of the behaviour of those from humans. A comparative perspective has enhanced our knowledge of human red cell pathophysiology Summary This review emphasises how studies on animal red cells have enriched our understanding of the behaviour of those from humans.
Kathleen M. Connolly, Pengyi Ding, Rasiqh Wadud, David C. Rees, John N. Brewin, John S. Gibson   +5 more
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

Cancer Science, EarlyView.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

Stimulation of erythroblast maturation in vitro by sphingolipids

Journal of Lipid Research, 1974
A lipid factor previously isolated from leukocytes and found to stimulate basophilic erythroblast formation in an in vitro system of incubated rabbit bone marrow cells has been analyzed by thin-layer chromatography, gas–liquid chromatography, and gas ...
R.B. Clayton, J.M. Cooper, Tore Curstedt, Jan Sjövall, Henry Borsook, J. Chin, A. Schwarz   +6 more
doaj   +1 more source