Results 111 to 120 of about 79,234 (272)

Positive Association Between the Cardiometabolic Index and the Risk of Male Biochemical Androgen Deficiency in Adults

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic disorders are associated with testosterone deficiency, and the cardiometabolic index (CMI) is a recently identified metabolic indicator. The relationship between male biochemical androgen deficiency (MBAD), a precursor to testosterone deficiency, and CMI remains unclear.
Shuai‐Shuai Mao   +2 more
wiley   +1 more source

Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. [PDF]

open access: yes, 2016
In this study, because excessive polycythemia is a predominant trait in some high-altitude dwellers (chronic mountain sickness [CMS] or Monge's disease) but not others living at the same altitude in the Andes, we took advantage of this human experiment ...
Appenzeller, Otto   +9 more
core  

Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]

open access: yes, 2018
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L   +8 more
core   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij   +11 more
wiley   +1 more source

The use of genes for performance enhancement: doping or therapy? [PDF]

open access: yes, 2011
Recent biotechnological advances have permitted the manipulation of genetic sequences to treat several diseases in a process called gene therapy. However, the advance of gene therapy has opened the door to the possibility of using genetic manipulation ...
Collares, T. F.   +4 more
core   +4 more sources

Anemia and retinopathy of prematurity: A narrative review

open access: yesPediatric Investigation, EarlyView.
Anemia in infants who are at greatest risk of developing severe retinopathy of prematurity is almost universal. There is plausible evidence in the literature correlating anemia with severe ROP. However, the relationship is complex, and further study is needed to better understand the potential molecular mechanisms for anemia‐associated ROP.
Minali Prasad   +3 more
wiley   +1 more source

A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Critical Illness

open access: yesFrontiers in Medicine, 2019
Burn injury has been shown to significantly dampen erythropoiesis in both burn patients and in murine models. Our previous findings elucidated the erythropoietin independent defects in red cell development stages involving erythroid progenitor production
Shirin Hasan   +7 more
doaj   +1 more source

Haemosporidian parasites (Apicomplexa, Haemosporida) of breeding common starling Sturnus vulgaris in Latvia

open access: yesWildlife Biology, EarlyView.
Migratory behaviour in seasonal environments affects host–pathogen relationships, especially for vector‐transmitted blood parasites of the order Haemosporida. The common starling Sturnus vulgaris is a short‐distance migrant where the north‐eastern European breeding population spend the non‐breeding season in temperate mild western Europe.
Antonija Rimša   +5 more
wiley   +1 more source

The Neural Crest as the First Production Site of the Erythroid Growth Factor Erythropoietin

open access: yesFrontiers in Cell and Developmental Biology, 2019
While the neural crest is considered the fourth germ layer that originates a variety of tissues during mammalian development, we recently discovered that some neural crest cells and neuroepithelial cells play a unique role in secreting a vital ...
Ikuo Hirano, Norio Suzuki
doaj   +1 more source

Purification and Characterization of Recombinant Darbepoetin Alfa from Leishmania tarentolae [PDF]

open access: yes, 2016
Darbepoetin alfa is a biopharmaceutical glycoprotein that stimulates erythropoiesis and is used to treat anemia, which associated with renal failure and cancer chemotherapy.
Ansari, J.   +8 more
core   +1 more source

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