Results 11 to 20 of about 85,288 (249)

Regulation of erythropoiesis: emerging concepts and therapeutic implications

open access: yesHematology, 2023
The process of erythropoiesis is complex and involves the transfer of cells from the yolk sac to the fetal hepar and, ultimately, to the bone marrow during embryonic development.
Pu Tang, Huaquan Wang
doaj   +2 more sources

Molecular mechanisms of regulation of erythropoiesis and stress erythropoiesis [PDF]

open access: yesMedicinski Podmladak
Erythropoiesis under basal conditions involves the continuous production of new erythrocytes at a constant rate. During the adult period, erythropoiesis takes place primarily in the bone marrow and has a substantial capacity.
Momčilović Sanja   +2 more
doaj   +2 more sources

Oxidation and erythropoiesis [PDF]

open access: yesCurrent Opinion in Hematology, 2019
Purpose of review Erythropoiesis is a complex multistep process going from committed erythroid progenitors to mature red cells. Although recent advances allow the characterization of some components of erythropoiesis, much still remains to be investigated particularly on stress erythropoiesis.
Matte A., De Franceschi L.
openaire   +4 more sources

Erythropoiesis: insights into pathophysiology and treatments in 2017

open access: yesMolecular Medicine, 2018
Erythropoiesis is a tightly-regulated and complex process originating in the bone marrow from a multipotent stem cell and terminating in a mature, enucleated erythrocyte.
Andrea Zivot   +3 more
doaj   +2 more sources

Transferrin Receptors in Erythropoiesis

open access: yesInternational Journal of Molecular Sciences, 2020
Erythropoiesis is a highly dynamic process giving rise to red blood cells from hematopoietic stem cells present in the bone marrow. Red blood cells transport oxygen to tissues thanks to the hemoglobin comprised of α- and β-globin chains and of iron ...
Cyrielle Richard, F. Verdier
semanticscholar   +2 more sources

Histone modifications in the regulation of erythropoiesis

open access: yesAnnals of Medicine
Introduction The pathogenesis of anemia and other erythroid dysphasia are mains poorly understood, primarily due to limited knowledge about the differentiation processes and regulatory mechanisms governing erythropoiesis.
Xiuyun Wu   +7 more
doaj   +2 more sources

Effects of empagliflozin on erythropoiesis in heart failure: data from the Empire HF trial

open access: yesEuropean Journal of Heart Failure, 2022
It remains unknown whether the consistently observed increase in haematocrit with sodium–glucose cotransporter 2 inhibitors is caused by diuresis‐associated haemoconcentration or increased erythropoiesis.
Camilla Fuchs Andersen   +15 more
semanticscholar   +1 more source

Ineffective erythropoiesis and its treatment.

open access: yesBlood, 2021
The erythroid marrow and circulating red blood cells (RBCs) are the key components of the human erythron. Abnormalities of the erythron that are responsible for anemia can be distinguished into 3 major categories, that is, erythroid hypoproliferation ...
M. Cazzola
semanticscholar   +1 more source

Molecular and cellular mechanisms that regulate human erythropoiesis

open access: yesBlood, 2021
Edited by Associate Editor Mario Cazzola, this review series highlights 3 specific areas of scientific and clinical advances in understanding disorders of red cell production.
A. Caulier, V. Sankaran
semanticscholar   +1 more source

Managing Anemia across the Stages of Kidney Disease in Those Hyporesponsive to Erythropoiesis-Stimulating Agents

open access: yesAmerican Journal of Nephrology, 2021
Background: Patients with CKD frequently have anemia that results from iron-restricted erythropoiesis and inflammation. Anemia of CKD is currently managed with iron supplements and erythropoiesis-stimulating agents (ESAs) to promote erythropoiesis and ...
M. Weir
semanticscholar   +1 more source

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