Results 41 to 50 of about 85,288 (249)
Physiological and Aberrant γ-Globin Transcription During Development
Frontiers in Cell and Developmental Biology, 2021 The expression of the fetal Gγ- and Aγ-globin genes in normal development is confined to the fetal period, where two γ-globin chains assemble with two α-globin chains to form α2γ2 tetramers (HbF). HbF sustains oxygen delivery to tissues until birth, when
Gloria Barbarani +4 more
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NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice
Haematologica, 2020 Nuclear receptor coactivator 4 (NCOA4) promotes ferritin degradation and Ncoa4-ko mice in a C57BL/6 background show microcytosis and mild anemia, aggravated by iron deficiency.
A. Nai +10 more
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Rare congenital Dyserythropoietic anemia of childhood: A case report
Clinical Case Reports, 2023 Congenital dyserythropoietic anemias (CDA) is a heterogeneous class of anemia of varying degrees of ineffective erythropoiesis and secondary hemochromatosis.
Hamzeh F. Al Hussien +4 more
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Hypoxia Pathway Proteins are Master Regulators of Erythropoiesis
International Journal of Molecular Sciences, 2020 Erythropoiesis is a complex process driving the production of red blood cells. During homeostasis, adult erythropoiesis takes place in the bone marrow and is tightly controlled by erythropoietin (EPO), a central hormone mainly produced in renal EPO ...
Deepika Watts +6 more
semanticscholar +1 more source
Anemias and iron deficiency in cancer patients
Клиническая онкогематология, 2013 Anemia is frequent in cancer patients and its incidence increases with chemotherapy. Anemia negatively impacts survival and accentuates fatigue in cancer patients.
V. V. Ptushkin
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Blood, 2017 In this issue of Blood, Alvarez-Dominguez et al reveal the strategies used to achieve precise but highly dynamic translational control of protein synthesis during red blood cell development.
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The role of cyclic nucleotide on fetal and neonantal erythropoiesis
, 1974 For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
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Erythropoiesis in lower-risk myelodysplastic syndromes and beta-thalassemia [PDF]
, 2023 The hematologic disorders myelodysplastic syndromes and beta-thalassemia are characterized by ineffective erythropoiesis and anemia, often managed with regular blood transfusions.
Cappellini, Maria Teresa +4 more
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Frontiers in Physiology, 2022 Erythrocytes represent at least 60% of all cells in the human body. During circulation, they experience a huge variety of physical and chemical stimulations, such as pressure, shear stress, hormones or osmolarity changes.
Marieke von Lindern +6 more
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Blood, 1971 Abstract Rabbits were rendered anemic by phlebotomy, by parenteral administration of phenylhydrazine and by phlebotomy coupled with transfusion of nonviable erythrocytes. Measurements were made of the number and iron uptake of immature erythroid cells, and the size and hemoglobin content of the circulating erythrocytes.
P, Jacobs, C A, Finch
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