Results 41 to 50 of about 60,520 (262)

Cish knockout mice exhibit similar outcomes to malaria infection despite altered hematopoietic responses

Frontiers in Microbiology, 2023
The Cytokine-inducible Src homology 2 domain-containing (CISH) protein is a negative feedback regulator induced by cytokines that play key roles in immunity and erythropoiesis.
Asha L. Lakkavaram, Saeed Maymand, Wasan Naser, Wasan Naser, Alister C. Ward, Alister C. Ward, Tania F. de Koning-Ward, Tania F. de Koning-Ward   +7 more
doaj   +1 more source

Oxidation and erythropoiesis [PDF]

, 2019
Purpose of review Erythropoiesis is a complex multistep process going from committed erythroid progenitors to mature red cells. Although recent advances allow the characterization of some components of erythropoiesis, much still remains to be ...
De Franceschi L., Matte A.
core   +1 more source

Erythropoiesis in lower-risk myelodysplastic syndromes and beta-thalassemia [PDF]

, 2023
The hematologic disorders myelodysplastic syndromes and beta-thalassemia are characterized by ineffective erythropoiesis and anemia, often managed with regular blood transfusions.
Cappellini, Maria Teresa, Taher, Ali T., Shah, Farrukh T., Verma, Amit K., Hermine, Olivier   +4 more
core   +1 more source

"Splenism" - the function of spleen, as the organ conducting the interrelation of the circulatory system and hematopoiesis

Patologìâ, 2013
On Wistar rats splenic involvement into the regulation of erythropoiesis was studied. Splenomegaly was reproduced for this both by ligation of splenic veins and transfusion of suspension of washed erythrocytes that leaded to the pronounced increase in ...
V.I. Filimonov, N.V. Stepanova, I.E. Sukhomlinova, M.A. Tikhonovskaya, G.I. Bessarab, D.A. Putilin, G.V. Pirtya   +6 more
doaj   +1 more source

Comprehensive Analysis of microRNAs in Human Adult Erythropoiesis

Cells, 2021
MicroRNAs (miRNAs) are small non-coding RNAs, which play an important role in various cellular and developmental processes. The study of miRNAs in erythropoiesis is crucial to uncover the cellular pathways that are modulated during the different stages ...
Aneesha Nath, Janakiram Rayabaram, Smitha Ijee, Abhirup Bagchi, Anurag Dutta Chaudhury, Debanjan Roy, Karthik Chambayil, Jyoti Singh, Yukio Nakamura, Shaji R. Velayudhan   +9 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The use of darbepoetin alpha in infants

Сеченовский вестник, 2019
Among the somatic pathology in young children, the most common is anemic syndrome. Until recently, the commonest method for correction of anemia was hemotransfusion, which allows to restore normal hemoglobin quickly, but has the high risk of ...
A. V. Shchegolev, G. Z. Sufianova, A. A. Sufianov, N. E. Ivanova, M. S. Khlestkina   +4 more
doaj   +1 more source

Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling

Biology, 2023
Ribosomes are the vital molecular machine for protein translation in a cell. Defects in several nucleolar proteins have been observed in human ribosomopathies.
Fang Liang, Xiaochan Lu, Biyu Wu, Yexin Yang, Wei Qin   +4 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Is There any Relationship Between the Repeated Complications of Sickle Cell Disease and the Potential Development of Acute Leukemia?

Oncology and Therapy
Sickle cell disease (SCD) is a severe monogenic hereditary hemoglobinopathy that is characterized by repeated clinical and biological manifestations able to generate stress erythopoiesis.
Giovanna Cannas, Mohamed Elhamri, Xavier Thomas   +2 more
doaj   +1 more source