Results 31 to 40 of about 85,288 (249)

Stress erythropoiesis: definitions and models for its study.

Experimental Hematology, 2020
Steady state erythropoiesis generates new erythrocytes at a constant rate, and it has an enormous productive capacity. This production is balanced by the removal of senescent erythrocytes by macrophages in the spleen and liver.
R. Paulson, S. Hariharan, J. Little
semanticscholar   +1 more source

The equilibrative nucleoside transporter 1 (ENT1) is critical for nucleotide homeostasis and optimal erythropoiesis.

Blood, 2021
The tight regulation of intracellular nucleotides is critical for the self-renewal and lineage specification of hematopoietic stem cells (HSCs). Nucleosides are major metabolite precursors for nucleotide biosynthesis and their availability in HSCs is ...
Mahmoud Mikdar, P. González-Menéndez, Xiao-li Cai, Yujin Zhang, Marion Serra, A. K. Dembélé, Anne-Claire Boschat, S. Sanquer, C. Chhuon, I. Guerrera, M. Sitbon, O. Hermine, Y. Colin, C. Le Van Kim, S. Kinet, N. Mohandas, Yang Xia, T. Peyrard, N. Taylor, S. Azouzi   +19 more
semanticscholar   +1 more source

Iron Mining for Erythropoiesis [PDF]

, 2022
Iron is necessary for essential processes in every cell of the body, but the erythropoietic compartment is a privileged iron consumer. In fact, as a necessary component of hemoglobin and myoglobin, iron assures oxygen distribution; therefore, a ...
Cairo, Gaetano, Gammella, Elena, Gaetano Cairo, Correnti, Margherita, Margherita Correnti, Recalcati, Stefania, Stefania Recalcati, Elena Gammella   +7 more
core   +1 more source

Role of apoptotic and anti-apoptotic mechanisms in erythroblast differentiation [PDF]

, 2004
The present study focuses on deciphering the differentiation mechanisms of erythroid cells. In particular, the involvement of apoptotic mechanisms in erythroblast differentiation and enucleation was examined.
Hristoskova, Sashka
core   +1 more source

Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Haematologica, 2014
Anemia of chronic disease is a multifactorial disorder, resulting mainly from inflammation-driven reticuloendothelial iron retention, impaired erythropoiesis, and reduced biological activity of erythropoietin.
Milan Theurl, Manfred Nairz, Andrea Schroll, Thomas Sonnweber, Malte Asshoff, David Haschka, Markus Seifert, Wolfgang Willenbacher, Doris Wilflingseder, Wilfried Posch, Anthony T. Murphy, Derrick R. Witcher, Igor Theurl, Günter Weiss   +13 more
doaj   +1 more source

Erythropoiesis Differences in Various Clinical Phases of Dengue Fever using Immature Reticulocyte Fraction Parameter

International Journal of Integrated Health Sciences, 2021
Objective: To determine the mechanism of erythropoiesis that led to anemia using the Immature Reticulocyte Fraction (IRF) parameter in various clinical phases of dengue fever.
Amaylia Oehadian, Putri Vidyaniati, Jeffery Malachi Candra, Uun Sumardi, Evan Susandi, Bachti Alisjahbana   +5 more
doaj   +1 more source

Clinical and Molecular Insights in Erythropoiesis Regulation of Signal Transduction Pathways in Myelodysplastic Syndromes and β-Thalassemia

International Journal of Molecular Sciences, 2021
Erythropoiesis regulation is essential in normal physiology and pathology, particularly in myelodysplastic syndromes (MDS) and β-thalassemia. Several signaling transduction processes, including those regulated by inositides, are implicated in ...
S. Parisi, C. Finelli, Antonietta Fazio, A. de Stefano, S. Mongiorgi, Stefano Ratti, A. Cappellini, A. Billi, L. Cocco, M. Follo, L. Manzoli   +10 more
semanticscholar   +1 more source

FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis

Frontiers in Cell and Developmental Biology, 2022
Primitive, neonatal and adult erythroid cells have been previously shown to have an active pentose phosphate pathway (PPP) that fuels various processes.
Anuntxi Monsalve, Isaac Canals, Leal Oburoglu   +2 more
doaj   +1 more source

Erythropoiesis and Hyperoxia

Experimental Biology and Medicine, 1973
SummaryExposure to a 50% oxygen environment produced a decrease in erythropoiesis which was paralleled by a decrease in plasma erythropoietic stimulating activity. Similar results were obtained following exposure to a 100% oxygen environment. Marrow depression produced by hyperoxia could be reversed by erythropoietic stimulants.
J W, Fletcher, N I, Gallagher, M A, Warnecke, R M, Donati   +3 more
openaire   +2 more sources

Patient and physician characteristics associated with erythropoiesis-stimulating agent use in patients with myelodysplastic syndromes

Haematologica, 2012
Patient and physician characteristics associated with use of erythropoiesis-stimulating agents in myelodysplastic syndrome patients have not yet been described.
Amy J. Davidoff, Sheila Weiss Smith, Maria R. Baer, Xuehua Ke, Jason M. Bierenbaum, Franklin Hendrick, Diane L. McNally, Steven D. Gore   +7 more
doaj   +1 more source