Results 21 to 30 of about 62,107 (294)
Research advances in erythrocyte regeneration sources and methods in vitro
Cell Regeneration, 2018 Erythrocytes (red blood cells, RBCs) facilitate gas exchange in the lungs and transport oxygen to the tissues. The human body must maintain erythrocyte regeneration to support metabolically active cells and tissues.
Shuming Sun, Yuanliang Peng, Jing Liu
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Erythropoiesis in preleukemia [PDF]
Blood, 1978 Bone marrow cells from seven patients with preleukemia and two with erythroleukemia were cultured in vitro to characterize erythropoiesis and erythropoietin responsiveness in these disorders. The methylcellulose plate technique was used to clone erythroid progenitors, and the results were compared to data obtained from studies on five healthy ...
H P, Koeffler, M J, Cline, D W, Golde
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Haematologica, 2014 Anemia of chronic disease is a multifactorial disorder, resulting mainly from inflammation-driven reticuloendothelial iron retention, impaired erythropoiesis, and reduced biological activity of erythropoietin.
Milan Theurl +13 more
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Physiological and Aberrant γ-Globin Transcription During Development
Frontiers in Cell and Developmental Biology, 2021 The expression of the fetal Gγ- and Aγ-globin genes in normal development is confined to the fetal period, where two γ-globin chains assemble with two α-globin chains to form α2γ2 tetramers (HbF). HbF sustains oxygen delivery to tissues until birth, when
Gloria Barbarani +4 more
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Rare congenital Dyserythropoietic anemia of childhood: A case report
Clinical Case Reports, 2023 Congenital dyserythropoietic anemias (CDA) is a heterogeneous class of anemia of varying degrees of ineffective erythropoiesis and secondary hemochromatosis.
Hamzeh F. Al Hussien +4 more
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Experimental Biology and Medicine, 1973 SummaryExposure to a 50% oxygen environment produced a decrease in erythropoiesis which was paralleled by a decrease in plasma erythropoietic stimulating activity. Similar results were obtained following exposure to a 100% oxygen environment. Marrow depression produced by hyperoxia could be reversed by erythropoietic stimulants.
J W, Fletcher +3 more
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Blood, 2009 AbstractMultisubunit complexes containing molecular chaperones regulate protein production, stability, and degradation in virtually every cell type. We are beginning to recognize how generalized and tissue-specific chaperones regulate specialized aspects of erythropoiesis.
Mitchell J, Weiss, Camila O, dos Santos
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Iron Mining for Erythropoiesis [PDF]
, 2022 Iron is necessary for essential processes in every cell of the body, but the erythropoietic compartment is a privileged iron consumer. In fact, as a necessary component of hemoglobin and myoglobin, iron assures oxygen distribution; therefore, a ...
Cairo, Gaetano +7 more
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Frontiers in Physiology, 2022 Erythrocytes represent at least 60% of all cells in the human body. During circulation, they experience a huge variety of physical and chemical stimulations, such as pressure, shear stress, hormones or osmolarity changes.
Marieke von Lindern +6 more
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Haematologica, 2012 Patient and physician characteristics associated with use of erythropoiesis-stimulating agents in myelodysplastic syndrome patients have not yet been described.
Amy J. Davidoff +7 more
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