Results 61 to 70 of about 85,288 (249)

Erythropoiesis in Hypothyroidism

Experimental Biology and Medicine, 1973
SummaryThe purpose of this study was to clarify the role which disordered iron metabolism and alterations in the homeostatic regulation of red cell production play in hypothyroid anemia.
R M, Donati, J W, Fletcher, M A, Warnecke, N I, Gallagher   +3 more
openaire   +2 more sources

Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis

Cell Reports, 2019
SUMMARY Human erythropoiesis serves as a paradigm of physiologic cellular differentiation. This process is also of considerable interest for better understanding anemias and identifying new therapies.
Leif S. Ludwig, C. Lareau, Erik L. Bao, Satish K. Nandakumar, C. Muus, J. Ulirsch, Kaitavjeet Chowdhary, Jason D. Buenrostro, N. Mohandas, X. An, Martin J. Aryee, A. Regev, V. Sankaran   +12 more
semanticscholar   +1 more source

Is There any Relationship Between the Repeated Complications of Sickle Cell Disease and the Potential Development of Acute Leukemia?

Oncology and Therapy
Sickle cell disease (SCD) is a severe monogenic hereditary hemoglobinopathy that is characterized by repeated clinical and biological manifestations able to generate stress erythopoiesis.
Giovanna Cannas, Mohamed Elhamri, Xavier Thomas   +2 more
doaj   +1 more source

Regulation of GATA1 levels in erythropoiesis

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2019
GATA1 is considered as the “master” transcription factor in erythropoiesis. It regulates at the transcriptional level all aspects of erythroid maturation and function, as revealed by gene knockout studies in mice and by genome‐wide occupancies in ...
L. Gutiérrez, N. Caballero, L. Fernández-Calleja, Elena Karkoulia, J. Strouboulis   +4 more
semanticscholar   +1 more source

Ineffective Erythropoiesis in β-Thalassemia [PDF]

, 2013
In humans, β-thalassemia dyserythropoiesis is characterized by expansion of early erythroid precursors and erythroid progenitors and then ineffective erythropoiesis.
Ivan Cruz Moura, Jean-Antoine Ribeil, Olivier Hermine, Michael Dussiot, Geneviève Courtois, Jean-Benoit Arlet   +5 more
core   +1 more source

Effect of Neopterin on Splenic Erythropoiesis in Mice

Pteridines, 2010
Neopterin is produced by monocytes and is a biomarker for inflammation. We recently found that neopterin induces stromal cells to produce cytokines that suppress erythropoiesis in the bone marrow of mice.
Tsuboi Isao, Harada Tomonori, Oshima Hideki, Aizawa Shin   +3 more
doaj   +1 more source

Fine‐Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation

Advanced Science, 2022
Lipid metabolism is essential for stemness maintenance, self‐renewal, and differentiation of stem cells, however, the regulatory function of cholesterol metabolism in erythroid differentiation is poorly studied.
Zhiyuan Lu, Lixia Huang, Yanxia Li, Yan Xu, Ruihao Zhang, Qian Zhou, Qi Sun, Yi Lu, Junjie Chen, Yuemao Shen, Jian Li, Baobing Zhao   +11 more
doaj   +1 more source

Erythropoietin in heart failure: effects beyond erythropoiesis [PDF]

, 2011
Erythropoietin in Heart Failure: Effects beyond Erythropoiesis Hartfalen is een ernstige cardiologische aandoening met een hoge mortaliteit en morbiditeit. Nieuwe behandelmethoden voor hartfalen zijn daarom gewenst. Het doel van dit proefschrift was het
Ruifrok, Willem-Peter Theodoor,, Ruifrok, Willem-Peter Theodoor   +1 more
core  

Serum erythropoietin and erythropoiesis in primary and secondary hyperparathyroidism: effect of parathyroidectomy

, 1991
Primary as well as secondary hyperparathyroidism may be associated with anemia, and parathyroidectomy (PTx) may improve or even heal it. The precise link between the two conditions is still matter of discussion.
Zins, B., Roullet, J. B., Kurtz, Armin, Sarfati, E., Zingraff, J., Ureña, P., Eckardt, Kai-Uwe, Drüeke, T., Roland, E.   +8 more
core   +1 more source

Iron Loading and Overloading due to Ineffective Erythropoiesis

Advances in Hematology, 2010
Erythropoiesis describes the hematopoietic process of cell proliferation and differentiation that results in the production of mature circulating erythrocytes.
Toshihiko Tanno, Jeffery L. Miller
doaj   +1 more source