Haemoglobin mass and running time trial performance after recombinant human erythropoietin administration in trained men [PDF]
, 2013 <p>Recombinant human erythropoietin (rHuEpo) increases haemoglobin mass (Hbmass) and maximal oxygen uptake (v˙ O2 max).</p> <p>Purpose: This study defined the time course of changes in Hbmass, v˙ O2 max as well as running time trial ...
A Lucia +51 more
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Haematologica, 2018 Primary familial and congenital polycythemia is characterized by erythropoietin hypersensitivity of erythroid progenitors due to germline nonsense or frameshift mutations in the erythropoietin receptor gene.
Florence Pasquier +11 more
doaj +1 more source
Prognostic significance of endogenous erythropoietin in long-term outcome of patients with acute decompensated heart failure [PDF]
, 2016 Aims Although previous reports suggest that an elevated endogenous erythropoietin (EPO) level is associated with worse clinical outcomes in chronic heart failure (HF) patients, the prognostic implication of EPO in patients with acute decompensated HF ...
Anand +27 more
core +1 more source
Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation [PDF]
, 1986 This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e.
Bauer, Christian +4 more
core +1 more source
Macrophages as novel target cells for erythropoietin
Haematologica, 2010 Background Our original demonstration of immunomodulatory effects of erythropoietin in multiple myeloma led us to the search for the cells in the immune system that are direct targets for erythropoietin.
Lilach Lifshitz +4 more
doaj +1 more source
Low oxygen tension primes aortic endothelial cells to the reparative effect of tissue-protective cytokines [PDF]
, 2015 Erythropoietin (EPO) has both erythropoietic and tissue-protective properties. The EPO analogues carbamylated EPO (CEPO) and pyroglutamate helix B surface peptide (pHBSP) lack the erythropoietic activity of EPO but retain the tissue-protective properties
A Anagnostou +57 more
core +1 more source
Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro [PDF]
, 1993 Since in juvenile rats the liver is the predominant site of erythropoietin (EPO) gene expression, we have used primary cultures of juvenile rat hepatocytes to establish and in vitro system for investigation of oxygen-dependent EPO formation.
Eckardt, Kai-Uwe +3 more
core +1 more source
Age-dependent expression of the erythropoietin gene in rat liver and kidneys [PDF]
, 1992 Using RNAse protection, we have made quantitative measurements of erythropoietin (EPO) mRNA in liver and kidneys of developing rats (days 1-54), to determine the relative contribution of both organs to the total EPO mRNA, to monitor changes which occur ...
Bauer, Christian +4 more
core +2 more sources
Distribution of erythropoietin producing cells in rat kidneys during hypoxic hypoxia [PDF]
, 1993 We have used in situ hybridization to determine the localization and distribution of cells expressing the erythropoietin (EPO) gene in kidneys of rats exposed to reduced oxygen tensions to characterize the control of renal EPO formation during hypoxic ...
Eckardt, Kai-Uwe +6 more
core +1 more source
Journal of Medical Case Reports, 2023 Background Absolute polycythemia can be primary or secondary. Erythropoietin-producing diseases (for example, hypoxia) are the major cause of secondary polycythemia. There are reports of polycythemia secondary to hydronephrosis. However, to our knowledge,
Yuriko Hajika +3 more
doaj +1 more source