Results 11 to 20 of about 78,398 (259)

Erythropoietin [PDF]

Cold Spring Harbor Perspectives in Medicine, 2013
During the past century, few proteins have matched erythropoietin (Epo) in capturing the imagination of physiologists, molecular biologists, and, more recently, physicians and patients. Its appeal rests on its commanding role as the premier erythroid cytokine, the elegant mechanism underlying the regulation of its gene, and its remarkable impact as a ...
openaire   +2 more sources

Macrophages as novel target cells for erythropoietin

Haematologica, 2010
Background Our original demonstration of immunomodulatory effects of erythropoietin in multiple myeloma led us to the search for the cells in the immune system that are direct targets for erythropoietin.
Lilach Lifshitz, Galit Tabak, Max Gassmann, Moshe Mittelman, Drorit Neumann   +4 more
doaj   +1 more source

Neuronal damage after moderate hypoxia and erythropoietin

Neurobiology of Disease, 2005
Both mild hypoxia and exogenous erythropoietin may protect the brain against subsequent severe hypoxia, and the conditioning effect of transient hypoxia is partly mediated by hypoxia-induced endogenous erythropoietin.
Astrid Weber, Mark Dzietko, Monika Berns, Ursula Felderhoff-Mueser, Uwe Heinemann, Rolf F. Maier, Michael Obladen, Chrissanthi Ikonomidou, Christoph Bührer   +8 more
doaj   +1 more source

Polycythemia with elevated erythropoietin production in a patient with a urinary stone and unilateral hydronephrosis: a case report

Journal of Medical Case Reports, 2023
Background Absolute polycythemia can be primary or secondary. Erythropoietin-producing diseases (for example, hypoxia) are the major cause of secondary polycythemia. There are reports of polycythemia secondary to hydronephrosis. However, to our knowledge,
Yuriko Hajika, Yuji Kawaguchi, Kenji Hamazaki, Yasuro Kumeda   +3 more
doaj   +1 more source

Erythropoietin reduces storage lesions and decreases apoptosis indices in blood bank red blood cells

Revista Brasileira de Hematologia e Hemoterapia, 2016
Background: Recent evidence shows a selective destruction of the youngest circulating red blood cells (neocytolysis) trigged by a drop in erythropoietin levels.
Oscar Andrés Penuela, Fernando Palomino, Lina Andrea Gómez   +2 more
doaj   +1 more source

Darbepoietin-alfa has comparable erythropoietic stimulatory effects to recombinant erythropoietin whilst preserving the bone marrow microenvironment

Haematologica, 2013
Erythropoiesis stimulating agents are widely used for the treatment of anemia. Recently, we reported erythroid expansion with impaired B lymphopoiesis and loss of trabecular bone in C57BL/6 mice following ten days of treatment with low-dose short acting ...
Sita R. Dewamitta, Megan R. Russell, Harshal Nandurkar, Carl R. Walkley   +3 more
doaj   +1 more source

Predictors of hyporesponsiveness to erythropoietin in prevalent hemodialysis patients and its association with mortality [PDF]

Revista Portuguesa de Nefrologia e Hipertensão, 2022
Introduction: Erythropoietin-stimulating agents hyporesponsiveness is common among hemodialysis patients. The aim was to analyze factors predictive of Erythropoietin-stimulating agent resistance and its association with mortality.
Marisa Roldão, Rui Duarte, Rachele Escoli, Hernâni Gonçalves, Flora Sofia, Karina Lopes   +5 more
doaj   +1 more source

Erythropoietin in the general population: reference ranges and clinical, biochemical and genetic correlates.

PLoS ONE, 2015
BackgroundAlthough erythropoietin has been used for decades in the treatment of anemia, data regarding endogenous levels in the general population are scarce.
Niels Grote Beverborg, Niek Verweij, Ijsbrand T Klip, Haye H van der Wal, Adriaan A Voors, Dirk J van Veldhuisen, Ron T Gansevoort, Stephan J L Bakker, Pim van der Harst, Peter van der Meer   +9 more
doaj   +1 more source

Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice. [PDF]

PLoS ONE, 2017
Tmprss6-mutated mask mice display iron deficiency anemia and high expression of hepcidin. The aim of the study was to determine the effect of erythropoietin administration on proteins participating in the control of iron homeostasis in the liver and ...
Jana Frýdlová, Zuzana Rychtarčíková, Iuliia Gurieva, Martin Vokurka, Jaroslav Truksa, Jan Krijt   +5 more
doaj   +1 more source

Serum erythropoietin levels, breast cancer and breast cancer-initiating cells

Breast Cancer Research, 2019
Background Cancer is frequently associated with tumor-related anemia, and many chemotherapeutic agents impair hematopoiesis, leading to impaired quality of life for affected patients.
Kruttika Bhat, Kiri Sandler, Sara Duhachek-Muggy, Claudia Alli, Fei Cheng, Neda A. Moatamed, Clara E. Magyar, Lin Du, Gang Li, Susan McCloskey, Erina Vlashi, Frank Pajonk   +11 more
doaj   +1 more source