Results 41 to 50 of about 187,553 (368)
Haematologica, 2013 Erythropoiesis stimulating agents are widely used for the treatment of anemia. Recently, we reported erythroid expansion with impaired B lymphopoiesis and loss of trabecular bone in C57BL/6 mice following ten days of treatment with low-dose short acting ...
Sita R. Dewamitta +3 more
doaj +1 more source
Predictors of hyporesponsiveness to erythropoietin in prevalent hemodialysis patients and its association with mortality [PDF]
Revista Portuguesa de Nefrologia e Hipertensão, 2022 Introduction: Erythropoietin-stimulating agents hyporesponsiveness is common among hemodialysis patients. The aim was to analyze factors predictive of Erythropoietin-stimulating agent resistance and its association with mortality.
Marisa Roldão +5 more
doaj +1 more source
Cold Spring Harbor Perspectives in Medicine, 2013 During the past century, few proteins have matched erythropoietin (Epo) in capturing the imagination of physiologists, molecular biologists, and, more recently, physicians and patients. Its appeal rests on its commanding role as the premier erythroid cytokine, the elegant mechanism underlying the regulation of its gene, and its remarkable impact as a ...
openaire +2 more sources
Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice. [PDF]
PLoS ONE, 2017 Tmprss6-mutated mask mice display iron deficiency anemia and high expression of hepcidin. The aim of the study was to determine the effect of erythropoietin administration on proteins participating in the control of iron homeostasis in the liver and ...
Jana Frýdlová +5 more
doaj +1 more source
Nature Communications, 2016 Inflammation resolution is an active process, the failure of which causes uncontrolled inflammation which underlies many chronic diseases. Therefore, endogenous pathways that regulate inflammation resolution are fundamental and of wide interest. Here, we
Bangwei Luo +9 more
semanticscholar +1 more source
Serum erythropoietin levels, breast cancer and breast cancer-initiating cells
Breast Cancer Research, 2019 Background Cancer is frequently associated with tumor-related anemia, and many chemotherapeutic agents impair hematopoiesis, leading to impaired quality of life for affected patients.
Kruttika Bhat +11 more
doaj +1 more source
Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
, 2014 The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander +4 more
core +3 more sources
Darbepoetin alfa given every 1 or 2 weeks alleviates anaemia associated with cancer chemotherapy. [PDF]
, 2002 In part A of this study, patients were randomised to cohorts receiving darbepoetin alfa at doses of 0.5 to 8.0 m.c.g x kg(-1) x wk(-1) or to a control group receiving epoetin alfa at an initial dose of 150 U x kg(-1) three times weekly.
Armstrong, S +10 more
core +2 more sources
Erythropoietin Pathway: A Potential Target for the Treatment of Depression
International Journal of Molecular Sciences, 2016 During the past decade, accumulating evidence from both clinical and experimental studies has indicated that erythropoietin may have antidepressant effects.
Chongyang Ma +6 more
semanticscholar +1 more source
Use of Recombinant Human Erythropoietin in Renal Anemia in Children
Bangabandhu Sheikh Mujib Medical University Journal, 2009 Erythropoietin is a hormone highly effective as like as natural erythropoietin to maintain target hemoglobin and hematocrit level in renal anemia. Its advantage over blood transfusion has been proved by improving the quality of life and decreasing ...
Habibur Rahman +4 more
doaj +1 more source