Results 41 to 50 of about 136,514 (310)
Стандартные образцы, 2017 Analysis of the publications devoted to the structure, functions, mechanism of action of erythropoietin is given in the article. Erythropoietin preparations derived from recombinant DNA technology are a mixture of isoforms with different biological ...
A. K. Yakovlev +9 more
doaj +1 more source
Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells [PDF]
, 2019 There are conflicting reports on the adverse effects of erythropoietin (EPO) for the management of cancer-associated anemia. The recognition that erythropoietin receptors (EPORs) are expressed outside the erythroid lineage and concerns that ...
Benchimol, Samuel +4 more
core +2 more sources
Semi-Blind and l1 Robust System Identification for Anemia Management [PDF]
arXiv, 2020 Chronic diseases such as cancer, diabetes, heart diseases, chronic kidney disease (CKD) require a drug management system that ensures a stable and robust output of the patient's condition in response to drug dosage. In the case of CKD, the patients suffer from the deficiency of red blood cell count and external human recombinant erythropoietin (EPO) is
arxiv
Advanced Science, EarlyView.A therapeutic strategy is proposed for periodontitis using extracellular vesicles derived from EPO‐stimulated macrophages (EPO‐EVs). This schema demonstrates how EPO‐EVs enhance the osteogenic activity of mBMSCs in an inflammatory environment by inhibiting EGFR.
Shuchen Liu +10 more
wiley +1 more source
Darbepoetin alfa given every 1 or 2 weeks alleviates anaemia associated with cancer chemotherapy. [PDF]
, 2002 In part A of this study, patients were randomised to cohorts receiving darbepoetin alfa at doses of 0.5 to 8.0 m.c.g x kg(-1) x wk(-1) or to a control group receiving epoetin alfa at an initial dose of 150 U x kg(-1) three times weekly.
Armstrong, S +10 more
core +2 more sources
Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, Accepted Article.Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Disease Models & Mechanisms, 2013 SUMMARY There is limited evidence that the tissue-protective effects of erythropoietin are mediated by a heterocomplex of the erythropoietin receptor and the β-common receptor (‘tissue-protective receptor’), which is pharmacologically distinct from the ...
Areeg I. Khan +8 more
doaj +1 more source
Erythropoietin level in normal and abnormal human seminal fluid
Андрология и генитальная хирургия, 2021 Background. There are not enough publications devoted to the study of erythropoietin in human sperm. According to the results of these studies, the erythropoietin takes part in the regulation of spermatogenesis, affecting the synthesis of hormones, in ...
D. Yu. Sosnin +2 more
doaj +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
BMEMat, EarlyView.The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source
Influence of hemoglobin level and dose of administered recombinant human beta erythropoietin on survival of hemodialysis patients [PDF]
Vojnosanitetski Pregled, 2011 Background/Aim. In patients with end-stage renal disease, treatment with erythropoietin lowers cardiovascular morbidity, improves quality of life and patient survival.
Knežević Violeta +5 more
doaj +1 more source