Results 61 to 70 of about 21,521 (247)

Cefdinir binding to a class A β‐lactamase revealed by serial cryo‐crystallography

Acta Crystallographica Section D, EarlyView.
Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gargi Gore, Andreas Prester, Kim Bartels, David von Stetten, Eike C. Schulz   +4 more
wiley   +1 more source

Prevalence and antimicrobial susceptibility of CTX‐M‐type‐producing Escherichia coli from a wildlife zoo in China

Veterinary Medicine and Science, 2022
Background Wildlife zoos provide the opportunity for children and adults to interact with animals, However, it's unknown that the risk of contact with animals, which carried zoonotic pathogens and antimicrobial resistant bacteria.
Ziyue Zeng, Jie Yang, Jinrong Gu, Zhihong Liu, Jufang Hu, Xiangyong Li, Xiaojun Chen, Zhiliang Sun, Jiyun Li   +8 more
doaj   +1 more source

Molecular epidemiology of CTX-M-producing escherichia coli isolates at a tertiary medical center in western pennsylvania [PDF]

, 2009
A combination of phenotypic and genotypic methods was used to investigate 70 unique Escherichia coli clinical isolates identified as producing extended-spectrum beta-lactamases (ESBLs) at a medical center in Pittsburgh, PA, between 2007 and 2008.
Adams-Haduch, Jennifer M., Doi, Yohei, Ewan, Lindsay, Muto, Carlene A., Pasculle, Anthony W., Paterson, David L., Sidjabat, Hanna E., Tian, Guo-Bao   +7 more
core   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

BJU International, EarlyView.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon, Asaad Ahmad, Natalie Lott, Alison Blatt   +3 more
wiley   +1 more source

Prevalence of extended-spectrum beta-lactamase-producing Klebsiella Pneumoniae isolates in nosocomial and community-acquired urinary tract infections [PDF]

, 2016
Background: Klebsiella pneumoniae is a family member of Enterobacteriaceae. Isolates of K. pneumoniae produce enzymes that cause decomposition of third generation cephalosporins.
Damavandi, M.S., Gholipour, A., Latifpour, M.   +2 more
core   +1 more source

Molecular analysis of the simultaneous production of two SHV-type extended-spectrum beta-lactamases in a clinical isolate of Enterobacter cloacae by using single-nucleotide polymorphism genotyping [PDF]

, 2005
Bacteria that simultaneously produce multiple extended-spectrum beta-lactamases are frequently isolated. We report an Enterobacter cloacae isolate, ES24, producing four different beta-lactamases (AmpC type beta-lactamase, TEM-1, SHV-7, and a novel ...
Szabo, Dóra, Melan, Melissa A., Hujer, Andrea M., Bonomo, Robert A., Hujer, Kristine M., Bethel, Christopher R., Kristof, Katalin, Paterson, David L.   +7 more
core   +1 more source

ESBL- FROM PETRI DISH TO THE PATIENT

Indian Journal of Medical Microbiology, 2006
Treatment of extended spectrum beta-lactamase (ESBL) producing strains of Enterobacteriaceae has emerged as a major challenge in hospitalised as well as community based patients. Infections due to ESBL producers range from uncomplicated urinary tract infection to life threatening sepsis.
openaire   +2 more sources

Proposed Meropenem Breakpoints for Interpretation of Antimicrobial Susceptibility Testing of Bacteria Isolated From Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Meropenem is a carbapenem antibiotic used infrequently in veterinary medicine. However, antimicrobial susceptibility testing standards are needed to monitor for resistance caused by carbapenem resistant Enterobacterales (CRE). The Clinical and Laboratory Standards Institute (CLSI) does not have veterinary‐specific carbapenem breakpoints for ...
Mark G. Papich, Marilyn N. Martinez
wiley   +1 more source

Surveillance of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Dairy Cattle Farms in the Nile Delta, Egypt [PDF]

, 2016
Introduction: Industrial livestock farming is a possible source of multi-resistant Gram-negative bacteria, including producers of extended spectrum beta-lactamases (ESBLs) conferring resistance to 3rd generation cephalosporins.
Daniel Weiß, Helmut Hotzel, Hosny El-Adawy, Ines Engelmann, Marwa F. E. Ahmed, Ralf Ehricht, Sascha D. Braun, Stefan Monecke   +7 more
core   +1 more source

Isolation of ESBL-producing gram-negative bacteria and in silico inhibition of ESBLs by flavonoids

Journal of Taibah University Medical Sciences, 2016
AbstractObjectiveTo evaluate nosocomial accounts of 426 extended spectrum β-lactamase (ESBL)-producing strains from 705 isolates of 9 pathogenic gram-negative bacteria in vitro. We analysed the genetic divergence of ESBLs by constructing a phylogenetic tree and modelled flavonoid inhibition of ESBLs with in silico molecular docking to determine ...
Swain, Shasank S., Padhy, Rabindra N.
openaire   +1 more source