Results 71 to 80 of about 700,150 (263)

Computational Health Engineering Applied to Model Infectious Diseases and Antimicrobial Resistance Spread

open access: yesApplied Sciences, 2019
Infectious diseases are the primary cause of mortality worldwide. The dangers of infectious disease are compounded with antimicrobial resistance, which remains the greatest concern for human health.
Mónica Cartelle Gestal   +2 more
doaj   +1 more source

Transparent UV‐Curable Self‐Sanitizing Coatings Applicable to Diverse Surfaces and High‐Touch Screens to Mitigate Deadly Pathogen Transmission

open access: yesAdvanced Functional Materials, EarlyView.
Development of a transparent, self‐sanitizing antimicrobial coating technology applicable to a wide range of materials and surfaces‐including touchscreens, transparent substrates, and metal, plastic, and glass‐regardless of pathogen type. The spray‐coated, UV‐cross‐linked imidazole‐based quaternary ammonium chloride materials provide broad‐spectrum ...
Surjith Kumaran   +6 more
wiley   +1 more source

Soluble Toll-Like Receptor 4 Impairs the Interaction of Shiga Toxin 2a with Human Serum Amyloid P Component

open access: yesToxins, 2018
Shiga toxin 2a (Stx2a) is the main virulence factor produced by pathogenic Escherichia coli strains (Stx-producing E. coli, STEC) responsible for hemorrhagic colitis and the life-threatening sequela hemolytic uremic syndrome in children.
Maurizio Brigotti   +8 more
doaj   +1 more source

3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization

open access: yesAdvanced Functional Materials, EarlyView.
Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono   +6 more
wiley   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu   +13 more
wiley   +1 more source

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

open access: yesAdvanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang   +12 more
wiley   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

open access: yesAdvanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee   +4 more
wiley   +1 more source

Photo‐Controlled Antibacterial Drug Release From DASA‐Coated Silica Particles for Improved Treatment of Wound Infections

open access: yesAdvanced Functional Materials, EarlyView.
Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc   +9 more
wiley   +1 more source

Milk Fat Globules Hamper Adhesion of Enterohemorrhagic Escherichia coli to Enterocytes: In Vitro and in Vivo Evidence

open access: yesFrontiers in Microbiology, 2018
Enterohemorrhagic Escherichia coli (EHEC; E. coli) are food-borne agents associated with gastroenteritis, enterocolitis, bloody diarrhea and the hemolytic-uremic syndrome (HUS).
Thomas Douëllou   +13 more
doaj   +1 more source

LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models

open access: yesAdvanced Functional Materials, EarlyView.
This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran   +5 more
wiley   +1 more source

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