Results 31 to 40 of about 752,160 (359)
Nature Communications, 2016 Several proteins are expressed at too low abundance in the Escherichia coli (E. coli) proteome to be detected by standard methods. Here, the authors create a microfluidics-based platform enabling single-molecule counting of low-abundance proteins by ...
Burak Okumus +11 more
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Producción de proteínas recombinantes de Plasmodium falciparum en Escherichia coli
Biomédica: revista del Instituto Nacional de Salud, 2016 Introducción. La producción de proteínas recombinantes es fundamental para el estudio funcional de las proteínas de Plasmodium falciparum. Sin embargo, las proteínas recombinantes de P.
Ángela Patricia Guerra +3 more
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Data in Brief, 2019 Crohn's disease (CD) is a type of inflammatory bowel disease (IDB). The endoscopic picture of Crohn's disease includes thickened submucosa, transmural inflammation, fissuring ulceration, and non-caseating granulomas.
Olga Bukato +7 more
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Rescue of Escherichia coli auxotrophy by de novo small proteins
eLife, 2023 Increasing numbers of small proteins with diverse physiological roles are being identified and characterized in both prokaryotic and eukaryotic systems, but the origins and evolution of these proteins remain unclear.
Arianne M Babina +8 more
doaj +1 more source
Inflating bacterial cells by increased protein synthesis. [PDF]
, 2015 Understanding how the homeostasis of cellular size and composition is accomplished by different organisms is an outstanding challenge in biology. For exponentially growing Escherichia coli cells, it is long known that the size of cells exhibits a strong ...
Basan, Markus +6 more
core +2 more sources
Quantifying the benefit of a proteome reserve in fluctuating environments. [PDF]
, 2017 The overexpression of proteins is a major burden for fast-growing bacteria. Paradoxically, recent characterization of the proteome of Escherichia coli found many proteins expressed in excess of what appears to be optimal for exponential growth.
Erickson, David W +4 more
core +3 more sources
Escherichia coli-derived virus-like particles in vaccine development
npj Vaccines, 2017 Recombinant virus-like particle-based vaccines are composed of viral structural proteins and mimic authentic native viruses but are devoid of viral genetic materials. They are the active components in highly safe and effective vaccines for the prevention
Xiaofen Huang +4 more
doaj +1 more source
Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]
, 2020 With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria +3 more
core +2 more sources
Essential Paralogous Proteins as Potential Antibiotic Multitargets in Escherichia coli
Microbiology Spectrum, 2022 Antimicrobial resistance threatens our current standards of care for the treatment and prevention of infectious disease. Antibiotics that have multiple targets have a lower propensity for the development of antibiotic resistance than those that have ...
Christine D. Hardy
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, 2005 The Min system in Escherichia coli directs division to the centre of the cell through pole-to-pole oscillations of the MinCDE proteins. We present a one dimensional stochastic model of these oscillations which incorporates membrane polymerisation of MinD
Elowitz M B +8 more
core +2 more sources