Results 181 to 190 of about 4,540 (215)

Glucosylation of esculetin by plant cell suspension cultures

Plant Cell, Tissue and Organ Culture, 1984
Cell suspension cultures of Lithospermum erythrorhizon, Gardenia jasminoides and Nicotiana tabacum were capable of glucosylating esculetin to esculin (7-hydroxycoumarin-6-O-β-D-glucoside). Especially, a culture strain of Lithospermum erythrorhizon was superior in the esculetin glucosylating capability; 40 to 50% of esculetin administered to the culture
M. Tabata, Y. Umetani, K. Shima, S. Tanaka   +3 more
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ChemInform Abstract: Improved Synthesis of Esculetin.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Electrochemical Behavior of Esculetin on Glassy Carbon Electrode

ECS Transactions, 2010
The electrochemical behavior of esculetin was investigated by cyclic voltammetry on glassy carbon electrode. The experimental conditions, such as supporting electrolyte and pH value, were tested for the electrochemical characterization of esculetin. It was shown that, in acetate buffer, the electrochemical behavior of esculetin had good reversibility.
Yatao Chen, Ping He, Yan Liang, Lanying Cheng, An Xia, Tinghong Zhang   +5 more
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Protective effects of esculetin against ovary ischemia–reperfusion injury model in rats

Journal of Biochemical and Molecular Toxicology, 2023
AbstractAimsOvarian ischemia–reperfusion (I/R) injury is a phenomenon that necessitates urgent intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young women. A large amount of free radical and oxidative damage as a result of I/R plays a role in the cause of the incident.
Mehmet Güvenç, Murat Yüksel, Tuncer Kutlu, Muhammed Etyemez, İshak Gökçek, Mustafa Cellat   +5 more
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Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis

Lipids and Lipid Metabolism, 1983
Esculetin (6,7-dihydroxycoumarin) showed inhibitory effects on 5- and 12-lipoxygenases of cloned mastocytoma cells. The half-inhibition dose (ID50) for each enzyme was 4 X 10(-6) and 2.5 X 10(-6) M, respectively. No inhibition at all, but rather a stimulating effect on prostaglandin synthesis, was observed, especially at higher doses of esculetin ...
T, Neichi, Y, Koshihara, S, Murota
exaly   +3 more sources

Esculetin and idebenone ameliorate galactose‐induced cataract in a rat model

Journal of Food Biochemistry, 2020
Cataract is the principal cause of blindness. The enzyme, aldose reductase (AR) is a key player in polyol pathway. Buildup of polyols and oxidative stress are the main causes of cataractogenesis. This study investigated the cytoprotective properties of esculetin and idebenone in galactose-induced cataract. Rats were partitioned into four groups each of
Nermin Abdel Hamid Sadik, Noha Ahmed El‐Boghdady, Nesreen Nabil Omar, Hager Abd Al‐Hamid   +3 more
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Esculetin Induces Apoptosis and Inhibits Adipogenesis in 3T3‐L1 Cells

Obesity, 2006
AbstractObjective: To determine the effects of esculetin, a plant phenolic compound with apoptotic activity in cancer cells, on 3T3‐L1 adipocyte apoptosis and adipogenesis.Research Methods and Procedures: 3T3‐L1 pre‐confluent preadipocytes and lipid‐filled adipocytes were incubated with esculetin (0 to 800 μM) for up to 48 hours.
Jeong-Yeh, Yang, Mary Anne, Della-Fera, Diane L, Hartzell, Cass, Nelson-Dooley, Dorothy B, Hausman, Clifton A, Baile   +5 more
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Evaluation of Percutaneous Absorption of Esculetin: Effect of Chemical Enhancers

Planta Medica, 2012
Percutaneous transdermal absorption of esculetin (6,7-dihydroxycoumarin), an oxidative damage inhibitor, was evaluated by means of in vitro permeation studies in which vertical Franz-type diffusion cells and pig ear skin were employed. To determine the absorption of esculetin, we validated a simple, accurate, precise, and rapid HPLC-UV method ...
Sergio, del Rio Sancho, César Eulogio, Serna Jiménez, María Aracely, Calatayud Pascual, Cristina, Balaguer Fernández, Andrés, Femenía Font, Encarna, Castillo García, Virginia, Merino, Alicia, López Castellano   +7 more
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Anti-inflammatory and peripheral analgesic activity of esculetin in vivo

Pharmacological Research Communications, 1988
Esculetin determined a reduction in oedema and granulocyte infiltration in the Croton oil ear test in vivo. The drug was able to inhibit Acethylcholine-writhing test and showed a LD50 of 1450 mg/kg i.p. and greater than 2000 mg/kg by mouth. In our experimental conditions, esculetin has an anti-inflammatory and analgesic effect.
TUBARO, AURELIA, DEL NEGRO P., RAGAZZI E., ZAMPIRON S., DELLA LOGGIA, ROBERTO   +4 more
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Esculetin regulates the phenotype switching of airway smooth muscle cells

Phytotherapy Research, 2019
Airway remodeling is one important feature of childhood asthma, which is one of the most common chronic childhood diseases. Phenotype switching of airway smooth muscle cells (ASMCs), defined as a reversible switching between contractile and proliferative phenotypes, plays an important role in the process of airway remodeling.
Chundan Xie, Yanyang Li, Jie Gao, Yingying Wang   +3 more
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