Results 161 to 170 of about 2,995 (191)
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Glucosylation of esculetin by plant cell suspension cultures
Plant Cell, Tissue and Organ Culture, 1984Cell suspension cultures of Lithospermum erythrorhizon, Gardenia jasminoides and Nicotiana tabacum were capable of glucosylating esculetin to esculin (7-hydroxycoumarin-6-O-β-D-glucoside). Especially, a culture strain of Lithospermum erythrorhizon was superior in the esculetin glucosylating capability; 40 to 50% of esculetin administered to the culture
M. Tabata +3 more
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Evaluation of Percutaneous Absorption of Esculetin: Effect of Chemical Enhancers
Planta Medica, 2012Percutaneous transdermal absorption of esculetin (6,7-dihydroxycoumarin), an oxidative damage inhibitor, was evaluated by means of in vitro permeation studies in which vertical Franz-type diffusion cells and pig ear skin were employed. To determine the absorption of esculetin, we validated a simple, accurate, precise, and rapid HPLC-UV method ...
Sergio, del Rio Sancho +7 more
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EFFECTS OF ESCULETIN AS A LIPOXYGENASE INHIBITOR IN SOYBEAN EXTRACTS
Journal of Food Lipids, 1997ABSTRACTThis study was designed to determine the ability of esculetin to inhibit lipoxygenase activity in soybean. Lipoxygenase was extracted from ground soybean using 0.1 M Tris‐HCl buffer (pH 8.6) and centrifuged at 3000 g for 15 min at 4C. The extract was mixed with different volumes of 0.05M esculetin solutions to provide 1.8 × 10−4M, 3.3 × 10−4M ...
KI‐TEAK LEE, DORRIS A. LILLARD
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ChemInform Abstract: Improved Synthesis of Esculetin.
ChemInform, 1995AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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HPLC Determination of Esculin and Esculetin in Rat Plasma for Pharmacokinetic Studies
Journal of Chromatographic Science, 2015An optimized, sensitive and validated reversed-phase high-performance liquid chromatography (RP-HPLC) method with UV detection is described for simultaneous determination of esculin and its aglycone, esculetin, in rat plasma. After addition of internal standard (chrysin), plasma samples were pretreated by solid-phase extraction and introduced into the ...
Shaheed Ur, Rehman +3 more
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Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease
Journal of Neuroscience Research, 2012AbstractThe production of reactive oxygen species and mitochondrial dysfunction in the brain are both associated with the progression of several neurodegenerative diseases, including Parkinson's disease. These characteristics are also observed when rodents are exposed to the neurotoxin 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP), a compound ...
Subramaniam, Sudhakar R +1 more
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Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes
Apoptosis, 2006Adipose tissue mass is determined by the volume and the number of adipocytes and is subjected to homeostatic regulation involving cell death mechanisms. We investigated the effects of esculetin, a coumarin compound, on apoptotic signaling in 3T3-L1 adipocytes.
Jeong-Yeh, Yang +2 more
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Esculetin regulates the phenotype switching of airway smooth muscle cells
Phytotherapy Research, 2019Airway remodeling is one important feature of childhood asthma, which is one of the most common chronic childhood diseases. Phenotype switching of airway smooth muscle cells (ASMCs), defined as a reversible switching between contractile and proliferative phenotypes, plays an important role in the process of airway remodeling.
Chundan Xie +3 more
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Esculetin; 6,7-dihydroxycoumarin
Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1977K. Ueno, N. Saito
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Esculetin in Alchemilla speciosa: identification and antimutagenic properties.
Die Pharmazie, 1997Quercetin, an ubiquitously occurring plant mutagen was detected and quantified in a methanolic extract prepared from the herb of Alchemilla speciosa BUSER (Rosaceae). However, the extract exhibited much less mutagenicity in Salmonella typhimurium than expected from its quercetin content.
O, Schimmer, H, Eschelbach
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