The possible anti-tumor actions and mechanisms of active metabolites from Cortex Fraxini. [PDF]
Cai B, Cai T, Feng Z, Zhu H.
europepmc +1 more source
Integrated foodomics and network pharmacology reveal functional food potential in tatsoi microgreens and baby greens. [PDF]
Xie Y +5 more
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Chemical Characterisation of <i>Cytisus striatus</i>: A Multi-Technique Approach Using GC-MS, LC-HRMS/MS, NIR, and FT-RAMAN. [PDF]
Caramelo D +4 more
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Functional genomic investigation of <i>CYP71AJ49</i> in <i>Peucedanum praeruptorum</i> Dunn: <i>Agrobacterium</i>-mediated overexpression reveals dual roles in drought adaptation and coumarin biosynthesis. [PDF]
Wang M +5 more
europepmc +1 more source
Analysis and identification of coumarins in different parts of <i>Chimonanthus salicifolius</i> and biosynthetic pathways prediction. [PDF]
Jiang Y, Ma X, Xu M, Xie T, Tong Y.
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ESCULETIN PREVENTS LIVER DAMAGE INDUCED BY PARACETAMOL AND CCL4
Esculetin, a phenolic compound found in Cichorium intybus and Bougainvllra spectabillis was investigated for its possible protective effect against paracetamol and CCl4-induced hepatic damage. Paracetamol produced 100% mortality at the dose of 1 g kg-1 in mice while pre-treatment of animals with esculetin (6 mg kg-1) reduced the death rate to 40%. Oral
Anwarul Hassan Gilani +2 more
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Induction of apoptosis by esculetin in human leukemia cells
European Journal of Pharmacology, 2001Esculetin, a coumarin compound, has been shown to exhibit antioxidant and anti-inflammatory effects. In the present study, esculetin was found to inhibit the survival of human promyelocytic leukemia HL-60 cells in a concentration-dependent and time-dependent manner.
Chia-Yih Chu +2 more
exaly +3 more sources
Electrochemical Behavior of Esculetin on Glassy Carbon Electrode
The electrochemical behavior of esculetin was investigated by cyclic voltammetry on glassy carbon electrode. The experimental conditions, such as supporting electrolyte and pH value, were tested for the electrochemical characterization of esculetin. It was shown that, in acetate buffer, the electrochemical behavior of esculetin had good reversibility.
Yatao Chen +5 more
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Selective inhibition of platelet lipoxygenase by esculetin
Lipids and Lipid Metabolism, 1982The effects of coumarin and its derivatives on rat platelet lipoxygenase and cyclooxygenase activities were studied. Esculetin (6,7-dihydroxycoumarin) was found to inhibit the lipoxygenase more strongly than the cyclooxygenase; its concentration for 50% inhibition (IC50) was 0.65 microM for platelet lipoxygenase and 0.45 mM for platelet cyclooxygenase.
Okuda Hiromichi
exaly +3 more sources

