Results 21 to 30 of about 7,313 (199)

ED90 of epidural esketamine with 0.075% ropivacaine for labor analgesia in nulliparous parturients: a prospective, randomized and dose-finding study

open access: yesFrontiers in Pharmacology, 2023
Background: Because it has been reported that racemic ketamine had a local anesthetic-sparing effect when used for epidural analgesia this would suggest the likelihood of a potential advantage (less pruritus) over opioid drugs.
Siwen Lou   +5 more
doaj   +1 more source

Esketamine improves propofol-induced brain injury and cognitive impairment in rats

open access: yesTranslational Neuroscience, 2022
As an intravenous anesthetic, propofol has been indicated to induce neurotoxicity in both animal and human brains. It is of great significance to better understand the potential mechanism of propofol-induced neurotoxicity to eliminate the side effects of
Xu Guiping   +5 more
doaj   +1 more source

Safety of esketamine nasal spray: Analysis of post-marketing reports submitted to the FDA adverse event reporting system in the first year on the market

open access: yesEuropean Psychiatry, 2021
Introduction The approval of the esketamine nasal spray for treatment-resistant depression in March 2019 by the Food and Drug Administration (FDA), and few months later by the European Medicine Agency, triggered a vivid debate and many concerns, mainly
C. Gastaldon   +3 more
doaj   +1 more source

Personalised Interventions - A Precision Approach for the Next Generation of Dietary Intervention Studies [PDF]

open access: yes, 2017
Acknowledgments The research of Baukje de Roos is supported by the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS). Lorraine Brennan acknowledges The European Research Council ERC (647783).
Brennan, Lorraine, de Roos, Baukje
core   +2 more sources

Ketamine: NMDA receptors and beyond [PDF]

open access: yes, 2016
Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi   +2 more
core   +2 more sources

Therapeutic environment for esketamine a policy [PDF]

open access: yes, 2023
This project aimed to develop a structured policy surrounding the therapeutic environment of esketamine to provide continuity of care and maximize therapeutic benefits while mitigating possible side effects of esketamine. A literature review for the most
Stewart, Sierra
core   +1 more source

Efficacy and safety comparison of esketamine-propofol with nalbuphine-propofol for upper gastrointestinal endoscopy in children: a multi-center randomized controlled trial

open access: yesFrontiers in Pediatrics, 2023
Background and AimsAnesthetics such as propofol, esketamine and nalbuphine are used during the upper gastrointestinal endoscopy to achieve and maintain the desired sedation level.
Xiaosu Zheng   +8 more
doaj   +1 more source

Potential ‘anti-cancer’ effects of esketamine on proliferation, apoptosis, migration and invasion in esophageal squamous carcinoma cells

open access: yesEuropean Journal of Medical Research, 2023
Background Esketamine, an N-methyl-D-aspartate receptor antagonist, is commonly used for anesthesia and analgesia clinically. It was reported to negatively regulate cell proliferation, metastasis and apoptosis in cancer cells, including lung cancer and ...
Chao Li   +3 more
doaj   +1 more source

Development and feasibility of a web application to monitor patients’ cancer-related pain [PDF]

open access: yes, 2017
Background: In the outpatient setting, pain management is often inadequate in patients with cancer-related pain, because of patient- and professional-related barriers in communication and infrequent contacts.
Baan, M.A.G. (Mathilde)   +2 more
core   +1 more source

Management of treatment-resistant depression with esketamine nasal spray: clinical questions for daily practice in Gulf Cooperation Council countries

open access: yesMiddle East Current Psychiatry, 2023
Background There is a high unmet need among patients with treatment-resistant depression (TRD) as treatment with standard therapies is associated with low response and remission rates and high rates of relapse.
Nahida Nayaz Ahmed   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy