Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer—the relationship with regulatory hypoxia-inducible factor-1α expression, tumor invasiveness, and patient prognosis [PDF]
Increased glucose uptake mediated by glucose transporters and reliance on glycolysis are common features of malignant cells. Hypoxia-inducible factor-1α supports the adaptation of hypoxic cells by inducing genes related to glucose metabolism.
Anna Krześlak +51 more
core +1 more source
Intratumoral heterogeneity of esophageal squamous cell carcinoma [PDF]
The advent of large scale genome characterization led to rapidly increasing knowledge of genetic landscapes of malignancies in recent years. Besides a difference in quantity of mutations between different entities, studies revealed as well a difference in the amount of mutations in varying locations of a single neoplastic lesion: the relation of ...
openaire +2 more sources
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi +9 more
wiley +1 more source
HIV infection and domestic smoke exposure, but not human papillomavirus, are risk factors for esophageal squamous cell carcinoma in Zambia: a case-control study [PDF]
(c) 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original ...
Asombang, AW +7 more
core +2 more sources
Pembrolizumab versus chemotherapy for patients with esophageal squamous cell carcinoma enrolled in the randomized KEYNOTE-181 trial in Asia [PDF]
Yanshuo Cao +27 more
openalex +1 more source
This prospective randomized trial evaluated whether prehabilitation, exercise and nutrition intervention, enhance skeletal muscle mass during neoadjuvant chemotherapy in older patients with esophageal cancer undergoing esophagectomy. We also investigated whether exercise alone was sufficient to increase skeletal muscle mass, and whether nutritional ...
Keijiro Sugimura +7 more
wiley +1 more source
Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. [PDF]
Cancer stem cells (CSCs) are considered to be the cause of tumor initiation, metastasis and recurrence. Additionally, CSCs are responsible for the failure of chemotherapy and radiotherapy.
Chen, Xinfeng +12 more
core
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar +5 more
wiley +1 more source
Multiple Meningocerebral Metastasis and Extensive Skull Metastasis from Squamous Cell Carcinoma of Esophagus: A Case Report and Review of Literature. [PDF]
Esophageal carcinoma rarely metastasizes to the brain. Although some studies have mentioned esoph ageal cancer with solitary brain metastasis or with meningocerebral metastasis or with skull metastasis, multiple meningocerebral metastasis and extensive ...
���������
core +3 more sources

