Results 51 to 60 of about 337,805 (303)

Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence

Nature Genetics, 2021
Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence that is not fully explained by known lifestyle and environmental risk factors. It has been speculated that an unknown exogenous exposure(s) could be responsible.
Sarah Moody, S. Senkin, S. Islam, Jingwei Wang, D. Nasrollahzadeh, Ricardo Cortez Cardoso Penha, Stephen Fitzgerald, E. Bergstrom, Joshua Atkins, Yudou He, Azhar Khandekar, K. Smith-Byrne, Christine Carreira, V. Gaborieau, Calli Latimer, Emily Thomas, Irina Abnizova, P. Bucciarelli, David Jones, J. Teague, B. Abedi-Ardekani, Stefano Serra, J. Scoazec, H. Saffar, F. Azmoudeh-Ardalan, M. Sotoudeh, A. Nikmanesh, H. Poustchi, Ahmadreza Niavarani, Samad Gharavi, Michael Eden, P. Richman, Lia S. Campos, R. C. Fitzgerald, L. Ribeiro, S. Soares-Lima, C. Dzamalala, B. Mmbaga, T. Shibata, D. Menya, A. Goldstein, N. Hu, R. Malekzadeh, A. Fazel, Valerie McCormack, J. Mckay, Sandra Perdomo, G. Scelo, E. Chanudet, Laura Humphreys, Ludmil B. Alexandrov, P. Brennan, Michael R. Stratton   +52 more
semanticscholar   +1 more source

RNA editing is induced by type I interferon in esophageal squamous cell carcinoma

Tumor Biology, 2017
In recent years, abnormal RNA editing has been shown to play an important role in the development of esophageal squamous cell carcinoma, as such abnormal editing is catalyzed by ADAR (adenosine deaminases acting on RNA). However, the regulatory mechanism
Jinyao Zhang, Zhaoli Chen, Zefang Tang, Jianbing Huang, Xueda Hu, Jie He   +5 more
doaj   +1 more source

High endothelin-converting enzyme-1 expression independently predicts poor survival of patients with esophageal squamous cell carcinoma

Tumor Biology, 2017
Patients with esophageal squamous cell carcinoma have poor survival and high recurrence rate, thus an effective prognostic biomarker is needed. Endothelin-converting enzyme-1 is responsible for biosynthesis of endothelin-1, which promotes growth and ...
Ching-Fang Wu, Ching-Tai Lee, Yao-Hung Kuo, Tzu-Haw Chen, Chi-Yang Chang, I-Wei Chang, Wen-Lun Wang   +6 more
doaj   +1 more source

LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma

Cell Death and Disease, 2021
Tumor cells require high levels of cholesterol for membrane biogenesis for rapid proliferation during development. Beyond the acquired cholesterol from low-density lipoprotein (LDL) taken up from circulation, tumor cells can also biosynthesize ...
Mingyue Tao, Jing Luo, Tong-Tong Gu, Xiao-juan Yu, Zhengyu Song, Yali Jun, H. Gu, Kairong Han, Xiujuan Huang, Weiyong Yu, Su’an Sun, Zhengwei Zhang, Lu Liu, Xiaofei Chen, Li Zhang, Chao Luo, Qi-long Wang   +16 more
semanticscholar   +1 more source

The long-term impact of tumor burden in pT3N0M0 esophageal squamous cell carcinoma

Medicine, 2019
The purpose of this study was to assess the impact of tumor burden on the survival of patients with pathologic T3N0M0 (pT3N0M0) esophageal squamous cell carcinoma (ESCC).
Tingting Li, Xiaobin Fu, L. Xiao, L. Su, Yaqing Dai, Qiwei Yao, Jiancheng Li   +6 more
semanticscholar   +1 more source

Assessment of Intratumoral and Peritumoral Computed Tomography Radiomics for Predicting Pathological Complete Response to Neoadjuvant Chemoradiation in Patients With Esophageal Squamous Cell Carcinoma

JAMA Network Open, 2020
Key Points Question Are peritumoral radiomics features extracted from pretreatment computed tomography images predictive of pathological complete response following neoadjuvant chemoradiation in patients with esophageal squamous cell carcinoma?
Yihuai Hu, C. Xie, Hong Yang, J. Ho, J. Wen, Lu-Jun Han, K. Chiu, Jianhua Fu, V. Vardhanabhuti   +8 more
semanticscholar   +1 more source

Toll-like receptors in esophageal cancer

Frontiers in Immunology, 2014
Esophageal squamous cell carcinoma and esophageal adenocarcinoma are cancers of high mortality. Esophageal adenocarcinoma develops through Barrett’s esophagus and columnar dysplasia, preceded by gastroesophageal reflux disease.
Joonas H Kauppila, Joonas H Kauppila, Joonas H Kauppila, Joonas H Kauppila, Katri S Selander, Katri S Selander   +5 more
doaj   +1 more source

Esophageal Neuroendocrine Carcinoma With Focal Squamous Cell Carcinoma Component

Journal of Investigative Medicine High Impact Case Reports, 2020
This study was about a 70-year-old man with progressive dysphagia. Esophagogastroduodenoscopy showed a 1.2-cm circumferential ulcerative mass at the level of 23 cm from the upper incisors in the upper esophagus.
Min Kyun Kang, Do Kyun Kang
doaj   +1 more source

Biobanking for Esophageal Squamous Cell Carcinoma

, 2020
Biobanking is important and fundamental for research and personalized medicine in patients with esophageal squamous cell carcinoma. The process often involves prospective collection of surgically obtained tissues (tissue banking) as well as serial blood samples (liquid biopsies) from the patients with esophageal squamous cell carcinoma.
openaire   +3 more sources

Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

Nature Medicine
Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results.
J. Qin, Liyan Xue, Anlin Hao, Xiaofeng Guo, Tao Jiang, Yunfeng Ni, Shuoyan Liu, Yujie Chen, Hongjing Jiang, Chen Zhang, M. Kang, Ji-hong Lin, Hecheng Li, Chengqiang Li, H. Tian, Lin Li, Junke Fu, Yong Zhang, Jianqun Ma, Xiaoyuan Wang, Maoyong Fu, Hao Yang, Zhaoyang Yang, Yongtao Han, Longqi Chen, Lijie Tan, Tianyang Dai, Yongde Liao, Weiguo Zhang, Bin Li, Qixun Chen, Shiping Guo, Y. Qi, Li Wei, Zhigang Li, Ziqiang Tian, X. Kang, Ruixiang Zhang, Yong Li, Zhen Wang, Xiankai Chen, Z. Hou, Rongrong Zheng, Wenqing Zhu, Jie He, Yin Li   +45 more
semanticscholar   +1 more source