Results 71 to 80 of about 446,222 (404)

Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck.

Gastroenterology, 2016
BACKGROUND & AIMS Some patients develop multiple squamous cell carcinomas (SCCs) in the upper aerodigestive tract, attributed to field cancerization; alcohol consumption has been associated with this process.
C. Katada, T. Yokoyama, T. Yano, K. Kaneko, I. Oda, Y. Shimizu, H. Doyama, T. Koike, K. Takizawa, M. Hirao, H. Okada, T. Yoshii, K. Konishi, Takenori Yamanouchi, T. Tsuda, T. Omori, N. Kobayashi, T. Shimoda, A. Ochiai, Y. Amanuma, S. Ohashi, T. Matsuda, H. Ishikawa, A. Yokoyama, M. Muto   +24 more
semanticscholar   +1 more source

RRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1

Advanced Biology, EarlyView.
The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.
Gang He, Yilong Wan, Yanbo Zhu, Bo Peng, Shengxiang Shao, Xinyi Zou, Zhenyu Han, Jiaxi Li, Sheng Ju, Xin Tong, Jun Zhao, Hansi Liang, Liuqing Zhang, Jiashi Xiong, Dong Jiang   +14 more
wiley   +1 more source

Paired Exome Analysis of Barrett’s Esophagus and Adenocarcinoma

Nature Genetics, 2015
Barrett's esophagus is thought to progress to esophageal adenocarcinoma (EAC) through a stepwise progression with loss of CDKN2A followed by TP53 inactivation and aneuploidy.
M. Stachler, A. Taylor-Weiner, Shouyong Peng, A. McKenna, A. Agoston, R. Odze, J. Davison, K. Nason, M. Loda, I. Leshchiner, C. Stewart, P. Stojanov, Sara Seepo, M. Lawrence, Daysha Ferrer-Torres, Jules Lin, A. Chang, S. Gabriel, E. Lander, D. Beer, G. Getz, S. Carter, A. Bass   +22 more
semanticscholar   +1 more source

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

Advanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula, Rosa M. Espinosa‐Marzal   +1 more
wiley   +1 more source

Clinical outcomes of EGFR-TKI in advanced lung squamous cell carcinoma and EGFR-TKI remodel tumor immune microenvironment

Annals of Medicine
Background Clinical data is scarce in epidermal growth factor receptor (EGFR)-mutated lung squamous cell carcinoma (LUSC), and the resistance mechanisms to EGFR-tyrosine kinase inhibitor (TKI) is rarely studied. This study aimed to assess the efficacy of
Zhixin Chen, Jiali Gong, Jing Chen, Lan Yang, Shumin Hu, Lingru Chen, Hongyang Lu   +6 more
doaj   +1 more source

Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo. [PDF]

, 2015
BACKGROUND: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency.
Alder, Hansjuerg, Chen, Hongping, Croce, Carlo M., Di Leva, Gianpiero, Fadda, Paolo, Farber, John L., Fong, Louise, Garofalo, Michela, Jiang, Yubao, Middleton, Justin, Naidu, Srivatsava, Selmi, Tommaso, Smalley, Karl J., Taccioli, Cristian, Tagliazucchi, Guidantonio Malagoli   +14 more
core   +1 more source

A formal theory for spatial representation and reasoning in biomedical ontologies [PDF]

, 2006
Objective: The objective of this paper is to demonstrate how a formal spatial theory can be used as an important tool for disambiguating the spatial information embodied in biomedical ontologies and for enhancing their automatic reasoning capabilities ...
Bittner, Thomas, Donnelly, Maureen, Rosse, Cornelius   +2 more
core   +2 more sources

Host‐Guest Inclusion Chemistry From Supramolecular Architecture Enabling Anti‐Biofouling Surfaces for Oesophagus Stents

Advanced Functional Materials, EarlyView.
A slippery coating with exceptional anti‐biofouling performance is developed using biocompatible materials for oesophagus stents. Host‐guest inclusion complex formation capabilities of FDA‐approved supramolecules, cyclodextrins are exploited, which significantly enhances the stability of the surface.
Jianhui Zhang, Haowei Wang, Sourabh Dogra, Xiaoye Zhao, Wenqing Chen, Arpan Gupta, Manish K. Tiwari, Vikramjeet Singh   +7 more
wiley   +1 more source

Pulmonary salivary gland tumor–hyalinizing clear cell carcinoma: a literature review

Diagnostic Pathology
Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is a very rare lung tumor that accounts for less than 0.09% of all primary lung tumors and has no specific epidemiology.
Xinyuan Wang, Shumin Hu, Hongyang Lu
doaj   +1 more source

Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry. [PDF]

, 2019
Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing upper endoscopy during
Berzin, T, Cash, B, Chang, K, DeMeester, S, Di Palma, JA, Diehl, D, Ganguly, E, Gonda, T, Gordon, S, Gress, F, Hagen, J, Hasan, M, Hawes, R, Hyder, S, Jobe, B, Joshi, V, Kahaleh, M, Kedia, P, Khara, H, Komatsu, Y, Konda, V, Lee, C, Lipham, J, Malik, Z, Mashimo, H, McKinley, M, Navaneethan, U, Oh, D, Pleskow, D, Poneros, J, Rodriguez, R, Rothstein, R, Samarasena, J, Sawhney, M, Schnoll-Sussman, F, Sejpal, DV, Sethi, A, Sharaiha, R, Sharzehi, K, Siddiqui, UD, Singh, S, Smith, MS, Tarnasky, P, Thakkar, S, Trindade, AJ, Wallace, M, Waxman, I, Wolfsen, H   +47 more
core