Results 91 to 100 of about 7,916,692 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Essential Spectrum of the Essentially Isometric Operator
Canadian Mathematical Bulletin, 2014 AbstractLet T be a contraction on a complex, separable, infinite dimensional Hilbert space and let σ(T) (resp. σe(T)) be its spectrum (resp. essential spectrum). We assume that T is an essentially isometric operator; that is, IH -T*T is compact. We show that if D\σ(T) ≠ Ø, then for every f from the disc-algebraσe(f(T)) = f(σe(T))where D is the open ...
openaire +2 more sources
, 2003 "A newsletter of the IDRC/MOH Tanzania Essential Health Interventions ...
Tanzania Essential Health Interventions Project
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
BiologyIn this study, 119 different coriander genotypes (38 different countries), including 114 genotypes and five cultivars, were undertaken to characterize the genotypes based on phenotypic, morphological, yield, and International Union for the Protection of ...
Abdurrahman Basol +2 more
doaj +1 more source
Comparative study of the design and chemical composition of heated tobacco products [PDF]
BIO Web of ConferencesHeated tobacco products (HTPs) are marketed as alternatives to conventional cigarettes and as products with potentially reduced harm. Despite the growing consumption of HTPs worldwide, their chemical composition and physical properties remain ...
Ivanova Tanya +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source