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Discovery of essential fatty acids
Dietary fat was recognized as a good source of energy and fat-soluble vitamins by the first part of the 20th century, but fatty acids were not considered to be essential nutrients because they could be synthesized from dietary carbohydrate.
Arthur A. Spector, Hee-Yong Kim
doaj +2 more sources
Essential Fatty Acids and Their Metabolites in the Pathobiology of Inflammation and Its Resolution. [PDF]
Arachidonic acid (AA) metabolism is critical in the initiation and resolution of inflammation. Prostaglandin E2 (PGE2) and leukotriene B4/D4/E4 (LTB4/LD4/LTE4), derived from AA, are involved in the initiation of inflammation and regulation of immune ...
Das UN.
europepmc +2 more sources
Seaweeds as Valuable Sources of Essential Fatty Acids for Human Nutrition. [PDF]
The overexploitation of terrestrial habitats, combined with the ever-growing demand for food, has led to the search for alternative food sources. The importance of seaweeds as food sources has been growing, and their potential as sources of fatty acids ...
Rocha CP +5 more
europepmc +2 more sources
Unsaturated Fatty Acids and Their Immunomodulatory Properties
Simple Summary Diet can influence human health in both positive and negative ways. Ω-3 polyunsaturated fatty acids have an overall positive effect on humans. The sources of these fatty acids are primarily plant seeds and fish.
Salvatore J. Coniglio +2 more
semanticscholar +1 more source
Acyl-CoA synthase ACSL4: an essential target in ferroptosis and fatty acid metabolism
Long-chain acyl-coenzyme A (CoA) synthase 4 (ACSL4) is an enzyme that esterifies CoA into specific polyunsaturated fatty acids, such as arachidonic acid and adrenic acid. Based on accumulated evidence, the ACSL4-catalyzed biosynthesis of arachidonoyl-CoA
Kaiyue Ding +6 more
semanticscholar +1 more source
Omega-9 fatty acids: potential roles in inflammation and cancer management
Omega-9 fatty acids represent one of the main mono-unsaturated fatty acids (MUFA) found in plant and animal sources. They are synthesized endogenously in humans, though not fully compensating all body requirements.
M. Farag, M. Gad
semanticscholar +1 more source
Omega‐3 polyunsaturated fatty acids (omega‐3 PUFAs), which are essential fatty acids that humans should obtain from diet, have potential benefits for human health.
Yawei Fu +7 more
semanticscholar +1 more source
Lipid-free Antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties [PDF]
Background: The hydatid disease parasite Echinococcus granulosus has a restricted lipid metabolism, and needs to harvest essential lipids from the host.
Córsico, Betina +5 more
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A stable essential fatty acid-deficient cell type, known as HepG2-EFD, was derived from the lipoprotein-producing human hepatoma cell line HepG2. These cells are particularly useful for quantitative studies involving essential fatty acids (n-6 and n-3 ...
EE Furth +4 more
doaj +1 more source
The adequate supply of essential fatty acids (EFA) to the body depends upon sufficient dietary intake and subsequent efficient intestinal absorption. Lipid malabsorption is not only a leading cause of EFA deficiency (EFAD), but also occurs secondarily to
D M Minich, R J Vonk, H J Verkade
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