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Essential Tremor

New England Journal of Medicine, 2000
Essential tremor (ET) is among the most common neurologic disorders. The traditional view of this disorder as a benign, monosymptomatic, familial condition is being replaced by a more complex view of ET as perhaps a family of diseases with etiologic, clinical, and pathologic heterogeneity.
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Essential Tremor

Medical Clinics of North America, 2019
Essential tremor is one of the most common movement disorders. It is characterized by a bilateral action tremor of the upper limbs. It may be accompanied by tremor of the head, voice, or lower limbs. Essential tremor is often present for years or decades before presentation and it progresses insidiously.
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‘Orthostatic tremor’ in familial‐essential tremor

Neurology, 1986
We studied a family with essential tremor of the arms. Some members also had tremor of the trunk and legs on standing, but not on walking, sitting, or reclining. Tremor was evoked, regardless of body or limb position, by strong tonic contraction of the appropriate muscles; it was a type of static postural tremor.
A S, Wee, S H, Subramony, R D, Currier
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Handedness and Essential Tremor

Archives of Neurology, 1985
In patients with essential tremor, a direct relationship was found between hand dominance and severity of hand tremor. A higher incidence of left-handedness was found in patients with essential tremor than in controls.
N, Biary, W, Koller
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Imaging essential tremor

Movement Disorders, 2010
AbstractTo investigate over time changes in striatal dopamine transporter (DAT), we performed two sequential N‐ω‐fluoropropyl‐2β‐carbomethoxy‐3β‐(4‐iodophenyl) tropane single photon computed tomography (SPECT) scans in 20 subjects with essential tremor (ET), in 13 with Parkinson disease (PD) and in 23 healthy controls (HC, one scan only).
Isaias IU   +10 more
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Genetics of essential tremor

Parkinsonism & Related Disorders, 2012
Essential tremor (ET) is a prevalent condition manifesting with progressive action tremor. Although ET was traditionally viewed as a sporadic disease, a significant proportion of cases report a positive family history of tremor. Autosomal dominant inheritance can be demonstrated in many families.
Jasińska-Myga, Barbara   +1 more
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METOPROLOL IN ESSENTIAL TREMOR

The Lancet, 1980
The tremor of a patient with debilitating essential tremor who could not take propranolol (because of severe asthma) was dramatically reduced when metoprolol tartrate was administered in standard doses. Metoprolol appears to be an excellent alternative antitremor drug to propranolol in such patients.
R P, Newman, L, Jacobs
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Orthostatic tremor: An essential tremor variant?

Movement Disorders, 1988
AbstractThree patients with a clear‐cut history of essential tremor of the upper limbs presented with the clinical features reported by Heilman as orthostatic tremor. Electromyographic findings included 6–8 Hz postural tremor in all four limbs. Highly synchronized 16 Hz rhythmic discharges were found in the legs upon standing.
S M, Papa, O S, Gershanik
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Genetics of essential tremor

Parkinsonism & Related Disorders, 2016
Essential tremor is one of the most common adult-onset movement disorders. While it is recognized that genes play a major role in ET with ≥50% of the affected individuals having a positive family history, identifying underlying genes in both monogenic and complex forms of ET has been a challenging task.
Tio M., Tan E.-K.
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Overdiagnosis of essential tremor

The Lancet, 1999
2but it did not carry the large invasivity plasmid and was rough for its O-antigen. No Shiga toxin producing Ec o l i w e r e detected in the patient’s stool but the S sonnei isolate (named CB7888) showed toxicity to cultured Vero cells and was positive for Stx or Stx1 but negative for Stx2 in a latex agglutination assay (VTEC-RPLA).
A, Schrag   +4 more
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