Results 71 to 80 of about 270,121 (304)
Enfrentamiento a la muerte por cuidadores informales de pacientes con cáncer en estado terminal
Acta Médica del Centro, 2021 Introducción: el aumento del número de personas con cáncer impone un reto a los servicios de salud y propicia que los cuidados paliativos se realicen en el espacio familiar; sin embargo, los cuidadores informales disponen de insuficiente información sobre la conveniencia de decir o no la verdad o cómo y cuándo hacerlo.
Juan Ricardo Sotés Martínez +4 more
openaire +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Nefrectomía Laparoscópica para Donación Renal.
Revista Guatemalteca de Urología, 2017 El trasplante renal no está al alcance de la gran mayoría de pacientes con enfermedad renal en estado terminal. El trasplante renal de donador vivo ha venido en aumento para disminuir el periodo de espera de trasplante; el inconveniente es que no está ...
Estuardo Polanco
doaj +1 more source
Confession and political normativity: control of subjectivity and production of the subject [PDF]
, 2015 The theme of confession, present in the reflection of Michel Foucault since the early 1960s, pursued the same direction of his researches from the late 1970s concerning the problem of government and the studies of governmentality. Under this perspective,
Avelino, Nildo
core +4 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Los memes como creaciones de imaginarios instituyentes [PDF]
, 2017 Es un trabajo terminal de grado desarrollado con rigor teórico y metodológico, claramente ubicado en los problemas de la visualidad contemporánea, y con un trabajo de campo interesante, que explora la pertinencia de trabajar con las actitudes en el ...
ARANDA SANCHEZ, JOSE MARIA +1 more
core
A level-set method for thermal motion of bubbles and droplets [PDF]
, 2016 Published under licence in Journal of Physics: Conference Series by IOP Publishing Ltd. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence.
Balcázar Arciniega, Néstor +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture [PDF]
, 2017 Malnutrition is very prevalent in geriatric patients with hip fracture. Nevertheless, its importance is not fully recognized. The objective of this paper is to review the impact of malnutrition and of nutritional treatment upon outcomes and mortality in ...
Malafarina, Vincenzo +6 more
core +2 more sources