Results 261 to 270 of about 195,068 (336)

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

open access: yesPhotochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman   +7 more
wiley   +1 more source

Utility of Cytochemical and Flow Cytometry Detection of Alkaline Phosphatase for Differential Diagnosis of CD34+ Acute Leukaemia in Canines

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Alkaline phosphatase (ALP) enzymatic activity has been proposed as a marker for distinguishing canine acute leukaemia (AL) subtypes (i.e., myeloid vs. lymphoid). However, ALP enzymatic activity has not been fully evaluated in CD34+ AL. Determine whether ALP enzymatic activity can differentiate CD34+ AL subtypes in dogs and distinguish CD34+ AL
Megan Aalto   +7 more
wiley   +1 more source

C1 esterase inhibitor (C1-INH) response as a supportive diagnostic criterion for patients with suspected hereditary angioedema with normal C1-INH. [PDF]

open access: yesWorld Allergy Organ J
Smith AM   +11 more
europepmc   +1 more source

Determination of Reference Intervals for Selected Liver Biomarkers With Focus on Pre‐ and Postanalytical Factors in Lactating Dairy Cattle

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Measurement of liver enzymes and metabolites for both clinically healthy and sick cattle is a routine part of dairy herd management. Reference intervals (RIs) are influenced by many variables, including pregnancy, breeding, and geographical variables, and can shift over time.
Anna Theile   +2 more
wiley   +1 more source

Topical Omidenepag Isopropyl Lowers Intraocular Pressure in Normal and Glaucomatous Cats: A Pilot Study

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To evaluate the effects of topical prostaglandin E2 receptor 2 (EP2) agonist, omidenepag isopropyl (OMDI), on intraocular pressure (IOP) and pupil diameter (PD) in normal cats and cats with feline congenital glaucoma (FCG). Animals Studied Ten FCG cats and 8 normal cats.
Kazuya Oikawa   +5 more
wiley   +1 more source

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