Results 81 to 90 of about 128,429 (343)
Purified human C1-esterase inhibitor is safe in acute relapses of neuromyelitis optica
Objective: To minimize complement-mediated damage in acute relapses of neuromyelitis optica (NMO) by adding treatment with a complement inhibitor, purified C1-esterase inhibitor, to the current standard of care (high-dose glucocorticoids).
M. Levy, M. Mealy
semanticscholar +1 more source
A hydrophilic type I phototherapeutic agent (NanoPcN8O) was developed which selectively responded to hypoxic tumor microenvironments and switched on type I photodynamic and photothermal effects as well as a photoacoustic signal for activatable photoacoustic imaging and tumor phototherapy.
Yuan‐Yuan Zhao+6 more
wiley +2 more sources
Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA
In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa+5 more
wiley +1 more source
Structure and evolution of neuronal wiring receptors and ligands
Abstract One of the fundamental properties of a neuronal circuit is the map of its connections. The cellular and developmental processes that allow for the growth of axons and dendrites, selection of synaptic targets, and formation of functional synapses use neuronal surface receptors and their interactions with other surface receptors, secreted ...
Elena Cortés+2 more
wiley +1 more source
Zaprionus indianus was first recorded in Brazil in 1999 and rapidly spread throughout the country. We have obtained data on esterase loci polymorphisms (Est2 and Est3), and analyzed them, using Landscape Shape Interpolation and the Monmonier Maximum ...
Luís Gustavo da Conceição Galego+1 more
doaj
Establishing the resistance of Myzus persicae (Sulzer) by molecular methods [PDF]
In two years of investigating resistance of the peach-potato aphid Myzus persicae (Sulzer) by molecular methods, several types of resistance were established in the majority of individuals from peach and tobacco in Serbia and Montenegro.
Vučetić Anđa+3 more
doaj +1 more source
Lactobacillus plantarum is a lactic acid bacteria that can be found in numerous fermented foods. Esterases from L. plantarum exert a fundamental role in food aroma.
M. Esteban-Torres+3 more
semanticscholar +1 more source
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang+9 more
wiley +1 more source
A workflow is proposed for the computational design of new‐to‐nature PET hydrolases by remodeling the protein scaffold. Starting from the functional motifs extracted from a template enzyme, designer enzymes are generated following four steps: scaffold remodeling, computational screening, experimental validation, and sequence refinement.
Yujing Ding+4 more
wiley +1 more source
Blue-Biotechnology and Biocleaning of Historic-Artistic Artifacts
The search for novel cleaning strategies in restoration procedures is growing fast. One innovation/innovative breakthrough in cleaning procedures is represented by the use of enzymes. This is due to the fact that their action is highly selective and they
Franco Palla
doaj +1 more source