Results 51 to 60 of about 805 (190)

Estetrol/drospirenon: Anticonceptiepil met een nieuw, ‘natuurlijk’ oestrogeen.

, 2022
De meeste orale hormonale anticonceptiva bevatten het synthetische oestrogeen ethinylestradiol. Drovelis® is een anticonceptiepil met een nieuw oestrogeen, estetrol, gecombineerd met het progestageen drospirenon. Estetrol is een oestrogeen dat van nature
Afd Pharmacoepi & Clinical Pharmacology, Heersche, Annemarie, Pharmacoepidemiology and Clinical Pharmacology, Truong-Nguyen, T.   +3 more
core  

Metal-free synthesis of an estetrol key intermediate under intensified continuous flow conditions

, 2023
peer reviewedEstetrol is a natural biogenic estrogen with a promising future in hormonal-dependent treatments and growing established markets for oral contraception.
Cornut, Damien, Monbaliu, Jean-Christophe, Pauline Bianchi, Damien Cornut, Dubart, Amaury, Moors, Maurane, Ampurdanés Vilanova, Jordi, Maurane Moors, Gilbert Duhirwe, Bianchi, Pauline, Jordi Ampurdanés Vilanova, Amaury Dubart, Duhirwe, Gilbert, Jean-Christophe M. Monbaliu   +13 more
core   +1 more source

Hemostasiologic safety of the estetrol-drospirenone combined oral contraceptive

Клинический разбор в общей медицине
Currently, realization of thrombotic events against the background of using hormonal contraception remains one of the controversial issues of today’s gynecology.
Mekan R. Orazov, Viktor E. Radzinskii, Evgenii D. Dolgov   +2 more
doaj   +1 more source

Estetrol/drospirenon: Contraceptive pill with a new, 'natural' estrogen.

, 2022
De meeste orale hormonale anticonceptiva bevatten het synthetische oestrogeen ethinylestradiol. Drovelis® is een anticonceptiepil met een nieuw oestrogeen, estetrol, gecombineerd met het progestageen drospirenon. Estetrol is een oestrogeen dat van nature
Heersche, Annemarie, Truong-Nguyen , T.
core  

Hepatotoxicity Associated with Labetalol Use: A Case Report with Systematic Review and Disproportionality Analysis Using FAERS

The Journal of Clinical Pharmacology, Volume 66, Issue 4, April 2026.
Abstract Labetalol is widely prescribed as a first‐line antihypertensive in pregnancy; however, rare but potentially severe idiosyncratic hepatotoxicity has been reported, with a disproportionately strong reporting signal for liver injury relative to other β‐blockers.
Emma D. Hendriksen, Michael Rieder, Elizabeth Urbantke   +2 more
wiley   +1 more source

The perfect molecule for hormonal contraception: Estetrol benefits. A review

Гинекология
The article addresses studies of estetrol (E4) use as part of combined oral contraceptives (COCs) and its various effects on the body. Despite the rapid recovery of fertility after discontinuation of COCs, their popularity is declining due to adverse ...
Elena A. Gorbunova, Inna A. Apolikhina
doaj   +1 more source

Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of Action

Drugs in R&D, 2023
Estetrol (E4) is the most recently described natural estrogen. It is produced by the human fetal liver during pregnancy and its physiological function remains unclear. E4 is the estrogenic component of a recently approved combined oral contraceptive.
Céline Gérard, Jean-Michel Foidart
doaj   +1 more source

Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Although estrogen receptor α (ERα) acts primarily as a transcription factor, it can also elicit membrane‐initiated steroid signaling. Pharmacological tools and transgenic mouse models previously highlighted the key role of ERα membrane ...
Emmanuel Guivarc'h, Mélissa Buscato, Anne‐Laure Guihot, Julie Favre, Emilie Vessières, Linda Grimaud, Jamal Wakim, Nada‐Joe Melhem, Rana Zahreddine, Marine Adlanmerini, Laurent Loufrani, Claude Knauf, John A. Katzenellenbogen, Benita S. Katzenellenbogen, Jean‐Michel Foidart, Pierre Gourdy, Françoise Lenfant, Jean‐François Arnal, Daniel Henrion, Coralie Fontaine   +19 more
doaj   +1 more source

Maintaining bone health by estrogen therapy in patients with advanced prostate cancer: a narrative review

Endocrine Connections, 2022
The purpose of androgen deprivation therapy (ADT) in prostate cancer (PCa), using luteinizing hormone-releasing hormone agonists (LHRHa) or gonadotrophin-releasing hormone antagonists, is to suppress the levels of testosterone.
Herjan J T Coelingh Bennink, Jan Krijgh, Jan F M Egberts, Maria Slootweg, Harm H E van Melick, Erik P M Roos, Diederik M Somford, Yvette Zimmerman, Iman J Schultz, Noel W Clarke, R Jeroen A van Moorselaar, Frans M J Debruyne   +11 more
doaj   +1 more source

ESTETROL: DESDE UN ESTRÓGENO FETAL HASTA EL TRATAMIENTO DE LA MENOPAUSIA

Revista Chilena de Obstetricia y Ginecología, 2009
Estetrol es un esferoide estrogénico sintetizado exclusivamente por el hígado fetal, que traspasa a la circulación materna por la placenta. Descrito por primera vez por Diczfalusy en 1965.
Marcelo Bianchi P
doaj