Results 101 to 110 of about 2,450,622 (319)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

DEVELOPMENT OF THE EVALUATION SYSTEM FOR FORMATION MASTER'S COMPETENCES IN CONTEXT OF THE CONCEPT OF CONSTRUCTIVE ALIGNMENT OF D. BIGGS

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article analyzes the shortcomings of the traditional (measuring) system for evaluating learning outcomes. The article reveals the advantage of a student-centered system for assessing the formation of competencies based on the concept of constructive ...
Nadezhda Klushina
doaj  

Neutrosophic Log-Gamma Distribution and its Applications to Industrial Growth [PDF]

open access: yesNeutrosophic Sets and Systems
This study suggests a novel statistical distribution known as the neutrosophic loggamma distribution (NLGD) for analyzing the interval value data. The proposed distribution is derived from the transformation method, utilizing the approach of neutrosophic
Fuad S. Al-Duais
doaj   +1 more source

A systematic review of software development cost estimation studies

open access: yes, 2007
This paper aims to provide a basis for the improvement of software estimation research through a systematic review of previous work. The review identifies 304 software cost estimation papers in 76 journals and classifies the papers according to research ...
Shepperd, MJ, Jørgensen, M
core   +1 more source

Piecewise convex function estimation: pilot estimators [PDF]

open access: yesThe Annals of Statistics, 1997
Given noisy data, function estimation is considered when the unknown function is known a priori to consist of a small number of regions where the function is either convex or concave. When the number of regions is unknown, the model selection problem is to determine the number of convexity change points.
openaire   +4 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Segmentation-Based Depth Correction Methods for Near Field iToF LiDAR in Motion State

open access: yesIEEE Open Journal of Vehicular Technology
This paper presents two approaches to enhance depth correction of the indirect time-of-flight (iToF) LiDAR sensors during a motion state, addressing the challenges of depth ambiguity and motion blur noise.
Mena Nagiub   +4 more
doaj   +1 more source

Paralleled two-pass hexagonal algorithm for motion estimation

open access: yes, 2005
This paper presents a paralleled two-pass hexagonal (TPA) algorithm constituted by linear hashtable motion estimation algorithm (LHMEA) and hexagonal search (HEXBS) for motion estimation.
Megson, G.M., Wu, Y.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Center-of-gravity velocity estimation using lower limb muscle forces during walking

open access: yesJournal of Biomechanical Science and Engineering
This study proposes a gait model that describes the relation between the lower limb muscle forces and the center-of-gravity (CoG) velocity in the forward, vertical, and lateral directions.
Ayuko SAITO   +4 more
doaj   +1 more source

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