Results 111 to 120 of about 3,026,616 (303)

Smoothed L-estimation of Regression Function [PDF]

open access: yes
The Nadaraya-Watson nonparametric estimator of regression is known to be highly sensitive to the presence of outliers in data.This sensitivity can be reduced, for example, by using local L-estimates of regression.Whereas the local L-estimation is ...
Cizek, P., Tamine, J., Härdle, W.K.
core  

Calibrated Weighting for Small Area Estimation

open access: yes, 2005
Calibrated weighting methods for estimation of survey population characteristics are widely used. At the same time, model-based prediction methods for estimation of small area or domain characteristics are becoming increasingly popular.
Chambers, R. L.
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Estimation of Differential Structures on Triangulated Surfaces

open access: yes, 1997
This paper presents a method for extracting differential structures on 3D surfaces and describes an algorithm for estimation of principal curvatures and principal directions from 3D scanned data.
V'aclav Hlav'ac. Estimation Of Differential   +3 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A comparative study on quantitative precipitation estimation based on GPM satellite and X-band phased-array weather radar

open access: yesFrontiers in Remote Sensing
This study investigates the performance of the Global Precipitation Measurement (GPM) satellite in comparison to the X-band Phased Array Weather Radar (XPAR) regarding precipitation measurement accuracy, focusing on radar echoes.
Yongyan Su   +8 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Decision Directed Channel Estimation Aided OFDM Employing Sample-Spaced and Fractionally-Spaced CIR Estimators

open access: yes, 2007
In this letter we characterize the substantial difference between two channel estimation approaches, namely the sample-spaced (SS) and the fractionally-spaced (FS) channel impulse response (CIR) estimators. The achievable performance of decision-directed
Akhtman, Jos, Hanzo, Lajos
core   +1 more source

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