Results 131 to 140 of about 2,450,622 (319)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Topics in estimation of quantum channels

open access: yes, 2010
A quantum channel is a mapping which sends density matrices to density matrices. The estimation of quantum channels is of great importance to the field of quantum information.
O'Loan, Caleb J.
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

FPGA-Accelerated ϵ-Greedy Ant Colony Optimisation for Maritime Bearings-Only Nonlinear Target Motion Analysis

open access: yesIEEE Access
Bearings-Only Target Motion Analysis (BOTMA) is challenging due to nonlinear dynamics, noisy angle-only sensing, and the nonconvexity of maximum-likelihood estimation (MLE).
Kyriakos M. Deliparaschos   +1 more
doaj   +1 more source

State estimation in chemometrics : the Kalman filter and beyond /

open access: yes
This unique text blends together state estimation and chemometrics for the application of advanced data-processing techniques. It further applies system theory in order to develop a modular framework to be implemented on computer for the development of ...
Thijssen, P. C.(Pierre Cornelis)
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Hardware-Aware Pruning for Efficient Inference on Embedded Devices

open access: yesIEEE Access
With more powerful yet efficient embedded devices and accelerators being available for Deep Neural Networks (DNNs), machine learning is becoming an integral part of edge computing. In application scenarios with real-time requirements and multiple sensors
Martin Lechner, Axel Jantsch
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

SAGE-Based Prediction of IQ Imbalance in OFDMA AF-FDR Uplink Relaying Systems

open access: yesIEEE Access
In orthogonal frequency division multiple access (OFDMA) systems, the in- and quadrature-phase imbalance (IQI) remains a critical impairment. Previous research has predominantly focused on non-cooperative settings, assuming that the modulation type is ...
Hala Mostafa   +2 more
doaj   +1 more source

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