Results 131 to 140 of about 5,969,672 (323)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
The Estimation of Pectin as Calcium Pectate and the Application of this Method to the Determination of the Soluble Pectin in Apples [PDF]
Marjory Harriotte Carré, Dorothy Haynes
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Nonparametric curve estimation with bernstein estimates
For the estimation of the regression function in a random design model a Bernstein type estimator is proposed. The author studies various local and global asymptotic properties of this estimator: Consistency and asymptotic normality at a fixed point are proved and an asymptotic expression for the expectation of the estimator is derived.
openaire +2 more sources
The isolation and estimation of urinary mucoproteins [PDF]
A. J. Anderson, N. F. Maclagan
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
The estimation of small amounts of formaldehyde liberated during the oxidation of carbohydrates and other substances with periodate [PDF]
J. F. O'Dea, R. A. Gibbons
openalex +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
Regular estimators for subclasses of linear estimators
The concept of regular estimator is due to \textit{J. Roy} and \textit{I. M. Chakravarti} [Ann. Math. Stat. 31, 392-398 (1960; Zbl 0093.158)]. For simple random sampling with or without replacement, regular estimators exist in the \(T_ 1\)-class of linear estimators.
openaire +3 more sources
Calibrated Weighting for Small Area Estimation
Calibrated weighting methods for estimation of survey population characteristics are widely used. At the same time, model-based prediction methods for estimation of small area or domain characteristics are becoming increasingly popular.
Chambers, R. L.
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