Results 1 to 10 of about 173,634 (281)

Estradiol regulates oxidative stress and angiogenesis of myocardial microvascular endothelial cells via the CDK1/CDK2 pathway

open access: yesHeliyon, 2023
Cardiovascular diseases remain the leading cause of death, morbidity, and disability. Recently, it has been reported that gonadal hormones such as estradiol can act on membrane receptors and activate intracellular signaling mechanisms, thereby altering ...
Ke Zhou   +5 more
doaj   +1 more source

A method to detect fulvestrant interference in estradiol in breast cancer patients

open access: yesEndocrine Connections, 2023
Background: Fulvestrant resembles estradiol in its structure. Reports have been published concerning fulvestrant measured as estradiol by the immunoassays. This may induce falsely elevated estradiol results and wrongly impact medical decisions.
Margarida Brito   +2 more
doaj   +1 more source

Interaction of estradiol and vitamin D with low skeletal muscle mass among middle-aged and elderly women

open access: yesBMC Women's Health, 2023
Background Since the connection between muscle atrophy and vitamin D and estradiol status ambiguous, this study was thus conducted to determine whether low skeletal muscle mass (SMM) in middle-aged and elderly women was affected by estradiol and vitamin ...
Jiaxing Zhang   +10 more
doaj   +1 more source

Serum estradiol level according to dose and formulation of oral estrogens in postmenopausal women

open access: yesScientific Reports, 2021
This study was performed to evaluate serum estradiol level in postmenopausal women using oral menopausal hormone therapy (MHT) with different doses and formulations of estrogens.
Soo-Min Kim   +3 more
doaj   +1 more source

Relationships between body mass index with oral estradiol dose and serum estradiol concentration in transgender adults undergoing feminising hormone therapy

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2020
Aim: Feminising hormone therapy with estradiol is used to align an individual’s physical characteristics with their gender identity. Given considerable variations in doses of estradiol therapy administered as gender-affirming hormone therapy (GAHT), we ...
Brendan J. Nolan   +9 more
doaj   +1 more source

Estradiol attenuates LPS-induced acute lung injury via induction of aquaporins AQP1 and AQP5

open access: yesEuropean Journal of Inflammation, 2021
Background Acute lung injury (ALI) is associated with increased inflammation and oxidative stress. Estradiol is produced by the ovaries and is the most active hormone of estrogen.
Xiaobo Wang   +3 more
doaj   +1 more source

Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway

open access: yesNutrition & Metabolism, 2021
Objectives The study of sex differences in hyperuricemia can provide not only a theoretical basis for this clinical phenomenon but also new therapeutic targets for urate-lowering therapy.
Lei Liu   +5 more
doaj   +1 more source

Evidence that 17alpha-estradiol is biologically active in the uterine tissue: Antiuterotonic and antiuterotrophic action

open access: yesReproductive Biology and Endocrinology, 2005
Background 17alpha-Estradiol has been considered as the hormonally inactive isomer of 17beta-estradiol. Recently, nongenomic (smooth muscle relaxation) and genomic (light estrogenic activity) effects of 17alpha-estradiol have been reported, but no ...
Navarrete Erika, Perusquía Mercedes
doaj   +1 more source

Distinct roles of estrone and estradiol in endothelial colony‐forming cells

open access: yesPhysiological Reports, 2023
Our current understanding of the relationship between estrogen and human endothelial colony‐forming cell (hECFC) function is based almost exclusively on studies investigating estradiol action at nuclear estrogen receptors.
Alicia Ivory, Andrew S. Greene
doaj   +1 more source

Predictor for supraphysiologic serum estradiol elevation on hCG triggering day of controlled ovarian stimulation using letrozole and gonadotropins in women with estrogen-dependent cancers.

open access: yesPLoS ONE, 2020
The objective of this study was to evaluate predicting factors for supraphysiologic serum estradiol elevation during controlled ovarian stimulation (COS) with administration of letrozole and gonadotropins in patients with estrogen-dependent cancer.
Sung Woo Kim   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy