Results 91 to 100 of about 309,036 (359)

Estrone and Estradiol Levels in Breast Cancer Patients Using Anastrozole Are Not Related to Body Mass Index [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2017
Objective: Obesity is associated with an increased risk for breast cancer. Recent studies have shown that aromatase inhibitors may be less effective in women with a high body mass index (BMI).
Eduardo Borges Coscia, Maricene Sabha, Marli Gerenutti, Francisco Carlos Groppo, Cristiane de Cássia Bergamaschi   +4 more
doaj   +1 more source

Testosterone Deficiency Is a Risk Factor for Severe COVID-19

Frontiers in Endocrinology, 2021
BackgroundMale sex is related to increased COVID-19 severity and fatality although confirmed infections are similarly distributed between men and women.
Lukas Lanser, Francesco Robert Burkert, Lis Thommes, Alexander Egger, Gregor Hoermann, Gregor Hoermann, Susanne Kaser, Germar Michael Pinggera, Markus Anliker, Andrea Griesmacher, Günter Weiss, Rosa Bellmann-Weiler   +11 more
doaj   +1 more source

Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]

, 2019
Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés, Camilletti, María Andrea, Diaz, Graciela Susana, Faraoni, Erika Yanil, Ratner, Laura Daniela, Recouvreux, Maria Victoria, Rulli, Susana Beatriz   +6 more
core   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Treatment of symptoms of the menopause: an endocrine society clinical practice guideline [PDF]

, 2015
Objective: The objective of this document is to generate a practice guideline for the management and treatment of symptoms of the menopause. Participants: The Treatment of Symptoms of the Menopause Task Force included six experts, a methodologist, and
Davis, Susan R., Gompel, Anne, Lumsden, Mary Ann, Murad, M. Hassan, Pinkerton, JoAnn V., Santen, Richard J., Stuenkel, Cynthia A.   +6 more
core   +1 more source

Oxidative Metabolism of Estradiol

Journal of Biological Chemistry, 1960
The metabolism of the estrogenic hormone is oxidative in nature in contrast to the reductive pathway for the neutral steroid hormones. It has been postulated that estrone is the precursor of estriol on the evidence that the required ketol intermediates are normal metabolites of the estrogenic hormone (2-4).
T. F. Gallagher, H. Leon Bradlow, Jack Fishman   +2 more
openaire   +3 more sources

Advanced Microfluidic‐Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring

Advanced Electronic Materials, EarlyView.
Microfluidic‐based wearable electrochemical sensors are transforming non‐invasive health monitoring through real‐time biochemical analysis of sweat, saliva, and interstitial fluid. This review explores advances in microfluidic design, fabrication, and sensor integration while addressing biofluid variability, material compatibility, and scalability.
Sehyun Park, Seongyeop Kim, Soojin Lee, Vladimir V. Tsukruk, SeungHyun Park, Hyo‐Ryoung Lim   +5 more
wiley   +1 more source

Aqueous solution interactions with sex hormone-binding globulin and estradiol: A theoretical investigation [PDF]

arXiv, 2017
Sex hormone-binding globulin (SHBG) is a binding protein that regulates availability of steroids hormones in the plasma. Although best known as steroid carrier, studies have associated SHBG in modulating behavioral aspects related to sexual receptivity.
arxiv  

Comprehensive genetic analysis of poorly differentiated gastric cancer in young females

Annals of Gastroenterological Surgery, EarlyView.
Although the involvement of female sex hormones in the development of poorly differentiated gastric cancer in young females is controversial, our detailed analysis using RNA‐seq suggested that the female sex hormone, β‐estradiol plays a role in the development of poorly differentiated gastric cancer in young females. Abstract Aim The reasons behind the
Nobuhiro Nakazawa, Takehiko Yokobori, Yohei Morishita, Akinobu Echigo, Reika Kawabata‐Iwakawa, Akiharu Kimura, Akihiko Sano, Makoto Sakai, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Endocannabinoid Signaling at Hypothalamic Steroidogenic Factor-1/Proopiomelanocortin Synapses Is Sex- and Diet-Sensitive

Frontiers in Molecular Neuroscience, 2018
We tested the hypotheses that steroidogenic factor (SF)-1 neurons in the hypothalamic ventromedial nucleus (VMN) provide sexually disparate, endocannabinoid (EC)- and diet-sensitive glutamatergic input onto proopiomelanocortin (POMC) neurons ...
Carolina Fabelo, Jennifer Hernandez, Rachel Chang, Sakara Seng, Natalia Alicea, Sharon Tian, Kristie Conde, Edward J. Wagner, Edward J. Wagner   +8 more
doaj   +1 more source