Results 11 to 20 of about 456,579 (295)
Neuroprotection by estradiol [PDF]
Progress in Neurobiology, 2001 This review highlights recent evidence from clinical and basic science studies supporting a role for estrogen in neuroprotection. Accumulated clinical evidence suggests that estrogen exposure decreases the risk and delays the onset and progression of Alzheimer's disease and schizophrenia, and may also enhance recovery from traumatic neurological injury
L. Garcia-Segura +2 more
semanticscholar +4 more sources
Estradiol-regulated microRNAs control estradiol response in breast cancer cells [PDF]
Nucleic Acids Research, 2009 Estradiol (E2) regulates gene expression at the transcriptional level by functioning as a ligand for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ).
P. Bhat-Nakshatri +10 more
semanticscholar +4 more sources
Estradiol, dopamine and motivation. [PDF]
Central Nervous System Agents in Medicinal Chemistry, 2015 The gonadal hormone estradiol modulates mesolimbic dopamine systems in the female rat. This modulatory effect is thought to be responsible for the observed effects of estradiol on motivated behaviors. Dopamine acting in the nucleus accumbens is thought to be important for the attribution of incentive motivational properties to cues that predict reward ...
Katie E. Yoest, J. Cummings, J. Becker
semanticscholar +4 more sources
Differential Effects of Estradiol and Estradiol-BSA Conjugates [PDF]
Endocrinology, 1999 The steroid 17beta-estradiol (E2) acts to modulate transcription through classical nuclear estrogen receptors (ER-alpha and ER-beta). However, E2 also induces a number of rapid responses (
Larry M. Mallis +4 more
openaire +3 more sources
Estradiol and the developing brain. [PDF]
Physiological Reviews, 2008 Estradiol is the most potent and ubiquitous member of a class of steroid hormones called estrogens. Fetuses and newborns are exposed to estradiol derived from their mother, their own gonads, and synthesized locally in their brains. Receptors for estradiol are nuclear transcription factors that regulate gene expression but also have actions at the ...
M. McCarthy
semanticscholar +3 more sources
Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway
Nutrition & Metabolism, 2021 Objectives The study of sex differences in hyperuricemia can provide not only a theoretical basis for this clinical phenomenon but also new therapeutic targets for urate-lowering therapy.
Lei Liu +5 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2022 Estradiol (E2) has been proven to be effective in treating perimenopausal depression (PD); however, the downstream signaling pathways have not been fully elucidated. Transient receptor potential channels 6 (TRPC6) plays a vital role in promoting neuronal
Qiaoli Song +12 more
doaj +1 more source
The Effect of Testosterone Replacement on Intramedullary, Inguinal and Visceral Fat in Ovariectomized Rats [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2020 Objective The present article aims to evaluate the impact of testosterone treatment on the expansion of visceral, subcutaneous and intramedullary adipose tissue of ovariectomized rats and the visceral and subcutaneous fat expression of peroxisome ...
Lorena Doretto da Silva +10 more
doaj +1 more source
Biotransformation and bioconcentration of steroid estrogens by Chlorella vulgaris [PDF]
, 2002 The biotransformation and bioconcentration of natural and synthetic steroid estrogens by Chlorella vulgaris were investigated using batch shaking experiments with incubation for 48 hours in the light or dark.
Lai, KM, Lester, JN, Scrimshaw, MD
core +2 more sources
Reproductive Biology and Endocrinology, 2005 Background 17alpha-Estradiol has been considered as the hormonally inactive isomer of 17beta-estradiol. Recently, nongenomic (smooth muscle relaxation) and genomic (light estrogenic activity) effects of 17alpha-estradiol have been reported, but no ...
Navarrete Erika, Perusquía Mercedes
doaj +1 more source