Results 81 to 90 of about 441,851 (391)

The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance

, 2019
Misfolded proteins in the endoplasmic reticulum (ER) activate the unfolded protein response (U PR), which enhances protein folding to restore homeostasis.
Borner, G., Schessner, J., Schmidt, R., Schuck, S.   +3 more
core   +1 more source

Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]

, 2018
Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara, BOSCARO, CARLOTTA, Cignarella, Andrea, Tedesco, Serena, Trenti, Annalisa, Trevisi, Lucia   +5 more
core   +2 more sources

Estradiol in elderly men [PDF]

The Aging Male, 2002
The role of estrogens in male physiology has become more evident, as a consequence of the discovery of human models of estrogen deficiency such as estrogen resistance or aromatase deficiency. In males, testosterone is the major source of plasma estradiol, the main biologically active estrogen, only 20% of which is secreted by the testes. Plasma estrone,
A. Vermeulen, S. Goemaere, I. Van Pottelberg, Jean Kaufman   +3 more
openaire   +3 more sources

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

Advanced Materials, EarlyView.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş, Mahshid Reshadsedghi, Mustafa Şen, Volkan Kılıç, Nesrin Horzum   +4 more
wiley   +1 more source

Urinary polycyclic aromatic hydrocarbon metabolites are positively related to serum testosterone levels of males and serum estradiol levels of females among U.S. adults

Frontiers in Endocrinology, 2022
BackgroundIt has been reported for several years that polycyclic aromatic hydrocarbons (PAHs) could disturb human endocrine function. However, there is still a short of consistent conclusion about the relationship between PAH exposure and levels of ...
Qiming Yuan, Kun Jin, Xianghong Zhou, Zhimei Qiu, Jiakun Li, Di Jin, Zilong Zhang, Chichen Zhang, Lu Yang, Yu Zhan, Shi Qiu, Qiang Wei   +11 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]

, 2003
Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE, Holden, DP, Nussey, SS, Whitley, GS   +3 more
core   +1 more source

Drastic Mechanochromic Luminescence Through Fluorescence–Phosphorescence Switching in a Heavy‐Atom‐Free Organoboron Compound

Advanced Optical Materials, EarlyView.
A new heavy‐atom‐free, donor–acceptor‐type organoboron luminophore has been synthesized, which exhibits red room‐temperature phosphorescence (RTP) in the crystalline state. Furthermore, the amorphous solid generated by grinding shows green thermally activated delayed fluorescence (TADF), displaying distinct mechanochromic luminescence (MCL) through ...
Yohei Adachi, Maho Kurihara, Shota Hosoya, Shota Terao, Masashi Nakamura, Yuichi Kitagawa, Yasuchika Hasegawa, Joji Ohshita   +7 more
wiley   +1 more source

Testosterone and Estradiol as Novel Prognostic Indicators for HBV-Related Acute-on-Chronic Liver Failure

Frontiers in Medicine, 2021
Background: HBV-related acute-on-chronic liver failure (HBV-ACLF) has a high short-term mortality and urgently needs an early warning system with simplicity and high accuracy.
Shuning Sun, Baoyan Xu, Wenting Tan, Xiaomei Xiang, Yi Zhou, Yunjie Dan, Yanzhi Guo, Zhaoxia Tan, Guohong Deng   +8 more
doaj   +1 more source

Effect of spironolactone and potassium canrenoate on cytosolic and nuclear androgen and estrogen receptors of rat liver [PDF]

, 1987
Spironolactone and potassium canrenoate are diuretics that are used widely for management of cirrhotic ascites. The administration of spironolactone frequently leads to feminization, which has been noted less frequently with the use of potassium ...
Alfredo Di Leo, Antonio Francavilla, Armanini, Aten, Bannister, Bellati, Boisselle, Bradford, Burton, Chopra, Clark, Duffy, Dupont, Eagon, Eagon, Eagon, Eagon, Farrell, Francavilla, Francavilla, Francavilla, Francesco Guglielmi, Fromatin, Giuseppe Fanizza, Greenblatt, Gustafsson, Gustafsson, Huffman, Kneifel, Lorenzo Polimeno, Loriaux, Marco, Menard, Michele Barone, Niewoehner, Norstedt, Patricia K. Eagon, Porter, Porter, Powell-Jones, Rifka, Rogerson, Scatchard, Serafini, Thomas E. Starzl, Turocy, Van Thiel   +46 more
core   +1 more source