Results 11 to 20 of about 1,175 (169)
Brain, Behavior, & Immunity - Health, 2021 HSP70 is one of the main molecular chaperones involved in the cellular stress response. Besides its chaperone action, HSP70 also modulates the immune response.
Camila Tiefensee Ribeiro +14 more
doaj +1 more source
Tetrahydrobiopterin: Beyond Its Traditional Role as a Cofactor
Antioxidants, 2023 Tetrahydrobiopterin (BH4) is an endogenous cofactor for some enzymatic conversions of essential biomolecules, including nitric oxide, and monoamine neurotransmitters, and for the metabolism of phenylalanine and lipid esters.
Tuany Eichwald +10 more
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Characterization and modulation of microglial phenotypes in an animal model of severe sepsis
Journal of Cellular and Molecular Medicine, Volume 24, Issue 1, Page 88-97, January 2020., 2020 Abstract We aim to characterize the kinetics of early and late microglial phenotypes after systemic inflammation in an animal model of severe sepsis and the effects of minocycline on these phenotypes. Rats were subjected to CLP, and some animals were treated with minocycline (10 ug/kg) by i.c.v. administration.
Monique Michels +11 more
wiley +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2020, Issue 1, 2020., 2020 Context. Chaptalia nutans (L.) Pol. (family: Asteraceae) is widely used in traditional medicine as laxative and anticough medications and especially in the traumatisms, wounds, and hemorrhages in topical preparations. Objective. This work was to evaluate the chemical constitution of the hydromethanolic (30/70 methanol‐water) macerating extract obtained
Letiele Bruck de Souza +9 more
wiley +1 more source
Estresse oxidativo e micronutrientes na hanseníase [PDF]
Revista de Nutrição, 2015 Objetivo Avaliar o estresse oxidativo, perfil antioxidante e de micronutrientes em pacientes portadores de hanseníase multibacilar e paucibacilar antes do tratamento poliquimioterápico. Métodos Analisaram-se 52 amostras de soro de pacientes portadores de hanseníase - 38 multibacilares e 14 paucibacilares -, usuários do ambulatório de dermatologia de um
OLIVEIRA, Fabiana Maciel de +5 more
openaire +3 more sources
Coagulation biomarkers and coronavirus disease 2019 phenotyping: a prospective cohort study
Thrombosis Journal, 2023 Background Because severe acute respiratory syndrome coronarivus 2 (SARS-CoV-2) leads to severe conditions and thrombus formation, evaluation of the coagulation markers is important in determining the prognosis and phenotyping of patients with COVID-19 ...
Emily Corneo +11 more
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Data in Brief, 2016 Jaboticaba (Plinia trunciflora (O. Berg) Kausel) is a Brazilian native berry, which presents high levels of polyphenols. Here we provide data related to the effects of the polyphenols-rich extract from jaboticaba on the cell viability, mitochondrial ...
Caroline Calloni +3 more
doaj +1 more source
Scientific Reports, 2017 The receptor for advanced glycation endproducts (RAGE) is a pattern-recognition receptor associated with inflammation in most cell types. RAGE up-regulates the expression of proinflammatory mediators and its own expression via activation of NF-kB. Recent
Juciano Gasparotto +9 more
doaj +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019 Objective. In this study, we evaluated the efficacy of simvastatin in the treatment of nonalcoholic steatohepatitis induced by methionine and choline‐deficient diet in mice and its possible effect on factors involved in the pathogenesis of the disease including oxidative stress and endoplasmic reticulum stress. Method.
Graziella Rodrigues +10 more
wiley +1 more source
Subacute Testicular Toxicity to Cadmium Exposure Intraperitoneally and Orally
Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019 The toxic effects of cadmium (Cd) on reproductive parameters are widely described in the literature. Experimental models often make use of the intraperitoneal route (i.p.), although human intoxication occurs preferentially by the oral route and can be continuous.
Viviane G. S. Mouro +8 more
wiley +1 more source