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Molecular mechanism of estrogen–estrogen receptor signaling [PDF]
Reproductive Medicine and Biology, 2016 17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct ...
Pelin Yaşar +4 more
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The role of estrogen and androgen receptors in bone health and disease
Nature Reviews Endocrinology, 2013 Stavros C Manolagas +2 more
exaly +3 more sources
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
Science, 2005 Eric R Prossnitz
exaly +2 more sources
Cells, 2021 Schizophrenia (SCZ) and bipolar disorder (BIP) are severe mental disorders with a considerable disease burden worldwide due to early age of onset, chronicity, and lack of efficient treatments or prevention strategies. Whilst our current knowledge is that
Denis Reis de Assis +9 more
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A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer
International Journal of Molecular Sciences, 2023 Breast cancer is the most common cancer and the deadliest among women worldwide. Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen and progesterone receptor positive), which accounts for two-thirds of tumors. Hormone
Léa Clusan +3 more
semanticscholar +1 more source
Hydrodynamic cavitation-enhanced activation of sodium percarbonate for estrogen removal
Water Science and Technology, 2023 The present paper investigated the potential of hydrodynamic cavitation (HC) as an effective tool for activating sodium percarbonate (SPC). The method's efficiency was demonstrated by effectively removing estrogens, which are pollutants that have adverse
Klára Odehnalová +6 more
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Gut microbial beta-glucuronidase: a vital regulator in female estrogen metabolism
Gut microbes, 2023 A growing amount of evidence has supported that gut microbiota plays a vital role in the reproductive endocrine system throughout a woman’s whole life, and gut microbial β-glucuronidase (gmGUS) is a key factor in regulating host estrogen metabolism ...
Shiwan Hu +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Osteoporosis is a serious health issue among aging postmenopausal women. The majority of postmenopausal women with osteoporosis have bone loss related to estrogen deficiency. The rapid bone loss results from an increase in bone turnover with an imbalance
Chui H Cheng, Li-Ru Chen, Kuo-Hu Chen
semanticscholar +1 more source
Human gut, breast, and oral microbiome in breast cancer: A systematic review and meta-analysis
Frontiers in Oncology, 2023 IntroductionDysbiosis characterises breast cancer through direct or indirect interference in a variety of biological pathways; therefore, specific microbial patterns and diversity may be a biomarker for the diagnosis and prognosis of breast cancer ...
May Soe Thu +12 more
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Frontiers in Cardiovascular Medicine, 2023 Inherited Arrhythmia Syndromes (IAS) including long QT and Brugada Syndrome, are characterized by life-threatening arrhythmias in the absence of apparent structural heart disease and are caused by pathogenic variants in genes encoding cardiac ion ...
Babken Asatryan, Andreas S. Barth
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