Results 1 to 10 of about 712,236 (344)

The impact of the gut microbiota on the reproductive and metabolic endocrine system

Gut Microbes, 2021
As the gut microbiota exerts various effects on the intestinal milieu which influences distant organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota plays a major role in the reproductive endocrine system throughout a
Xinyu Qi, Chuyu Yun, Yanli Pang, Jie Qiao   +3 more
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Estrogen Biosynthesis and Signal Transduction in Ovarian Disease

Frontiers in Endocrinology, 2022
Estrogen mainly binds to estrogen receptors (ERs) to regulate menstrual cycles and reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled estrogen receptor (GPER) mRNA could be detected in ovary, suggesting that they play an ...
Xue-Ling Xu, Zheng-Yuan Huang, Kun Yu, Jun Li, Xiang-Wei Fu, Shou-Long Deng   +5 more
doaj   +1 more source

UBE2C Overexpression Aggravates Patient Outcome by Promoting Estrogen-Dependent/Independent Cell Proliferation in Early Hormone Receptor-Positive and HER2-Negative Breast Cancer

Frontiers in Oncology, 2020
We previously showed that UBE2C mRNA expression is significantly associated with poor prognosis only in patients with hormone receptor (HR)+/human epidermal growth factor receptor 2 (HER2)– breast cancer.
Yu-Jin Kim, Gyunghwa Lee, Jinil Han, Kyoung Song, Joon-Seok Choi, Yoon-La Choi, Yoon-La Choi, Yoon-La Choi, Young Kee Shin, Young Kee Shin, Young Kee Shin   +10 more
doaj   +1 more source

Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium

Frontiers in Cell and Developmental Biology, 2022
Fibroblasts have been shown to be one of the essential players for mammary gland organization. Here, we identify two major types of mouse mammary gland fibroblasts through single-cell RNA sequencing analysis: Dpp4+ fibroblasts and Dpp4- fibroblasts. Each
Ryohei Yoshitake, Gregory Chang, Kohei Saeki, Kohei Saeki, Desiree Ha, Xiwei Wu, Jinhui Wang, Shiuan Chen   +7 more
doaj   +1 more source

Using Circadian Rhythm Patterns of Continuous Core Body Temperature to Improve Fertility and Pregnancy Planning

Journal of Circadian Rhythms, 2020
Objective: Review relationships among circadian clocks, core body temperature (CBT), and fertility in women. Methods: Scoping literature review. Results: Circadian clocks are a ubiquitous adaptation to the most predictable environmental events – the ...
Wade W. Webster, Benjamin Smarr
doaj   +1 more source

Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain

Frontiers in Endocrinology, 2012
Kisspeptin was originally found as a peptide product of Kiss1gene and is now supposed to be an essential central regulator of reproduction in mammals. However, there is now a growing body of evidence to suggest that kiss2, the paralogous gene for kiss1 ...
Shinji eKanda, Yoshitaka eOka
doaj   +1 more source

Human Umbilical Cord Blood Cells or Estrogen may be Beneficial in Treating Heatstroke

Taiwanese Journal of Obstetrics & Gynecology, 2007
This current review summarized animal models of heatstroke experimentation that promote our current knowledge of therapeutic effects on cerebrovascular dysfunction, coagulopathy, and/or systemic inflammation with human umbilical cord blood cells (HUCBCs)
Sheng-Hsien Chen, Kuo-Feng Huang, Mao-Tsun Lin, Fong-Ming Chang   +3 more
doaj   +1 more source

Estrogen administration modulates hippocampal GABAergic subpopulations in the hippocampus of trimethyltin-treated rats

Frontiers in Cellular Neuroscience, 2015
Given the well-documented involvement of estrogens in the modulation of hippocampal functions in both physiological and pathological conditions, the present study investigates the effects of 17-beta estradiol (E2) administration in the rat model of ...
Valentina eCorvino, Valentina eDi Maria, Elisa eMarchese, Wanda eLattanzi, Filippo eBiamonte, Fabrizio eMichetti, Maria Concetta eGeloso   +6 more
doaj   +1 more source

Effect of Local Estrogen on Repairing Tympanic Membrane Perforation [PDF]

Iranian Journal of Otorhinolaryngology, 2020
Introduction: Tympanoplasty is a surgical treatment of tympanic membrane perforation. Many efforts have been made to increase the success rate of tympanoplasty. Some studies confirmed the positive role of estrogen in wound healing.
Behrouz Barati, Golfam Mehrparvar, Matin Ghazizadeh   +2 more
doaj   +1 more source

MicroRNAs in the key events of systemic lupus erythematosus pathogenesis

Biomedical Papers, 2016
Background: Small non-coding RNA molecules (miRs) are involved in immune cell maturation and function and might influence immunopathological processes of systemic lupus erythematosus (SLE) pathogenesis.
Marketa Husakova
doaj   +1 more source