Results 181 to 190 of about 741,345 (366)
Reproductive history and cardiometabolic disease: the role of endogenous estrogen exposure across the lifespan in postmenopausal women. [PDF]
Zhu Y +10 more
europepmc +1 more source
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni +14 more
wiley +1 more source
Estrogen Modulation of B Cell Immunity: Implications for HIV Control and Therapeutic Strategies. [PDF]
Kasibante J +3 more
europepmc +1 more source
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu +9 more
wiley +1 more source
Estrogen-dependent effects of vagotomy and endogenous opioids on temporomandibular joint-responsive neurons in trigeminal subnucleus caudalis. [PDF]
Tashiro A +3 more
europepmc +1 more source
Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay +3 more
wiley +1 more source
NRF2 expression level and estrogen function in BRCA1-mutated breast cancer. [PDF]
Derismahafi Z +6 more
europepmc +1 more source

