Results 21 to 30 of about 16,304 (50)

Ovariectomy-induced hormone deprivation aggravates Aβ1-42 deposition in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of Alzheimer’s disease

Frontiers in Endocrinology, 2022
Alzheimer’s disease is the most common type of dementia, being highly prevalent in elderly women. The advanced progression may be due to decreased hormone synthesis during post-menopause as estradiol and progesterone both have neuroprotective potentials.
Szidónia Farkas, Szidónia Farkas, Adrienn Szabó, Adrienn Szabó, Adrienn Szabó, Bibiána Török, Bibiána Török, Csenge Sólyomvári, Csilla Lea Fazekas, Csilla Lea Fazekas, Csilla Lea Fazekas, Krisztina Bánrévi, Pedro Correia, Pedro Correia, Pedro Correia, Tiago Chaves, Tiago Chaves, Tiago Chaves, Dóra Zelena, Dóra Zelena   +19 more
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Menopause and development of Alzheimer’s disease: Roles of neural glucose metabolism and Wnt signaling

Frontiers in Endocrinology, 2022
Late onset Alzheimer´s disease (AD) is a neurodegenerative disease with gender differences in its onset and progression, being the prevalence predominant in women and at an earlier age than in men. The pathophysiology of the menopausal condition has been
Paulina Villaseca, Pedro Cisternas, Nibaldo C. Inestrosa, Nibaldo C. Inestrosa   +3 more
doaj   +1 more source

Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview

Cells
The endometrium is crucial for the perpetuation of human species. It is a complex and dynamic tissue lining the inner wall of the uterus, regulated throughout a woman’s life based on estrogen and progesterone fluctuations.
Isabelle Dias Da Silva, Vincent Wuidar, Manon Zielonka, Christel Pequeux   +3 more
doaj   +1 more source

Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome

Frontiers in Neuroscience, 2022
Women are disproportionately affected by Alzheimer's disease (AD), yet little is known about sex-specific effects on the development of AD in the Down syndrome (DS) population.
Elizabeth J. Andrews, Alessandra C. Martini, Elizabeth Head, Elizabeth Head   +3 more
doaj   +1 more source

Role of Estrogen and Other Sex Hormones in Brain Aging. Neuroprotection and DNA Repair

Frontiers in Aging Neuroscience, 2017
Aging is an inevitable biological process characterized by a progressive decline in physiological function and increased susceptibility to disease. The detrimental effects of aging are observed in all tissues, the brain being the most important one due ...
Sandra Zárate, Sandra Zárate, Tinna Stevnsner, Ricardo Gredilla   +3 more
doaj   +1 more source

Serum levels of 17β-estradiol in ovariectomized rats fed young-coconut-juice and its effect on wound healing [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2006
Exogenous estrogens such as 17β-estradiol (E2) can lower the risk of dementia in postmenopausal women (PMS), but can also increase the risk of serious side effects.
Boonsirm Withyachumnarnkul, Uraporn Vongvatcharanon, Nisaudah Radenahmad, James R. Connor   +3 more
doaj  

A Case Report of Hyperestrogenism in Prader-Willi Syndrome

AACE Clinical Case Reports, 2022
Objective: Prader-Willi syndrome (PWS) is associated with multiple endocrinopathies, including hypogonadism. The mechanism underlying hypogonadism in PWS is thought to be secondary to hypothalamic dysfunction, primary gonadal defect, or a combination of ...
Isabella Albanese, MDCM, MS, Natasha Garfield, MDCM   +1 more
doaj  

Age-Related Increases in Benign Paroxysmal Positional Vertigo Are Reversed in Women Taking Estrogen Replacement Therapy: A Population-Based Study in Taiwan

Frontiers in Aging Neuroscience, 2017
Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo. Numerous investigations have reported an increased BPPV incidence in females and in the aged population.
Ding-Hao Liu, Ding-Hao Liu, Chia-Hua Kuo, Chia-To Wang, Ch-Chih Chiu, Tzeng-Ji Chen, Tzeng-Ji Chen, De-Kuang Hwang, De-Kuang Hwang, Chung-Lan Kao, Chung-Lan Kao   +10 more
doaj   +1 more source

Glucose Metabolism in Turner Syndrome

Frontiers in Endocrinology, 2019
Turner syndrome (TS) is one of the most common female chromosomal disorders. The condition is caused by complete or partial loss of a single X chromosome. Adult patients with TS have a high prevalence of diabetes mellitus (DM).
Lin Sun, Yao Wang, Tong Zhou, Xue Zhao, Yingxuan Wang, Guixia Wang, Xiaokun Gang   +6 more
doaj   +1 more source

Effect of exposure to typical phthalate esters on estrogen homeostasis during pregnancy

Shanghai yufang yixue, 2022
ObjectiveTo study the relationship between the exposure to two kinds of phthalate esters （PAEs） ［Di-N-butyl phthalate，（DBP） and Di-（2-ethylhexyl）phthalate （DEHP）］ and estrogen homeostasis in pregnant women.MethodsIn 2021， we classified the Jiading ...
WU Linying, YANG Zichen, XUAN Dongliang, WANG Yuanping, TIAN Jing, WANG Yi, HAN Minghui, WANG Hexing, PENG Qian, JIANG Qingwu   +9 more
doaj   +1 more source