Results 21 to 30 of about 924,304 (411)

Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain

open access: yesFrontiers in Endocrinology, 2012
Kisspeptin was originally found as a peptide product of Kiss1gene and is now supposed to be an essential central regulator of reproduction in mammals. However, there is now a growing body of evidence to suggest that kiss2, the paralogous gene for kiss1 ...
Shinji eKanda, Yoshitaka eOka
doaj   +1 more source

Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group.

open access: yesJournal of the American Medical Association (JAMA), 1998
CONTEXT Observational studies have found lower rates of coronary heart disease (CHD) in postmenopausal women who take estrogen than in women who do not, but this potential benefit has not been confirmed in clinical trials.
S. Hulley   +6 more
semanticscholar   +1 more source

Human Umbilical Cord Blood Cells or Estrogen may be Beneficial in Treating Heatstroke

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2007
This current review summarized animal models of heatstroke experimentation that promote our current knowledge of therapeutic effects on cerebrovascular dysfunction, coagulopathy, and/or systemic inflammation with human umbilical cord blood cells (HUCBCs)
Sheng-Hsien Chen   +3 more
doaj   +1 more source

Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β.

open access: yesEndocrinology, 1998
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation domain.
G. Kuiper   +7 more
semanticscholar   +1 more source

Estrogen administration modulates hippocampal GABAergic subpopulations in the hippocampus of trimethyltin-treated rats

open access: yesFrontiers in Cellular Neuroscience, 2015
Given the well-documented involvement of estrogens in the modulation of hippocampal functions in both physiological and pathological conditions, the present study investigates the effects of 17-beta estradiol (E2) administration in the rat model of ...
Valentina eCorvino   +6 more
doaj   +1 more source

Effect of Local Estrogen on Repairing Tympanic Membrane Perforation [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2020
Introduction: Tympanoplasty is a surgical treatment of tympanic membrane perforation. Many efforts have been made to increase the success rate of tympanoplasty. Some studies confirmed the positive role of estrogen in wound healing.
Behrouz Barati   +2 more
doaj   +1 more source

MicroRNAs in the key events of systemic lupus erythematosus pathogenesis

open access: yesBiomedical Papers, 2016
Background: Small non-coding RNA molecules (miRs) are involved in immune cell maturation and function and might influence immunopathological processes of systemic lupus erythematosus (SLE) pathogenesis.
Marketa Husakova
doaj   +1 more source

Influence of Estrogen on the NSCLC Microenvironment: A Comprehensive Picture and Clinical Implications

open access: yesFrontiers in Oncology, 2020
Lung cancer mortality represents the leading cause of cancer related deaths in the United States and worldwide. Almost half of these deaths occur in female patients, making lung cancer the most common cause of cancer mortality in women with a higher ...
Tanner Smida   +4 more
doaj   +1 more source

Sequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation [PDF]

open access: yesPhys. Rev. Lett. 96, 198102 (2006), 2006
In human cells, estrogenic signals induce cyclical association and dissociation of specific proteins with the DNA in order to activate transcription of estrogen-responsive genes. These oscillations can be modeled by assuming a large number of sequential reactions represented by linear kinetics with random kinetic rates.
arxiv   +1 more source

Different approaches to unveil biomolecule configurations and their mutual interactions [PDF]

open access: yesAnalytical Letters 54, no.1-2, 40-56 (2020), 2020
A novel technique was demonstrated that overcome important drawbacks to crosslink cells by irradiation with ultrashort UV laser pulses (L-crosslinking). To use this technique coupled to Chromatin ImmunoPrecipitation (ChIP) in a high throughput context, a pre-screening fast method needs to be implemented to set up suitable irradiation conditions of the ...
arxiv   +1 more source

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