Results 231 to 240 of about 276,776 (266)

The standardization of estrogen receptors

The Journal of Steroid Biochemistry and Molecular Biology, 1993
Tumour estrogen receptor (ER) status may determine the medical treatment of a patient with breast cancer; yet inter-laboratory results can vary markedly, particularly when absolute cut-offs in fmol/mg cytosol protein are used. The use of standardized log units is proposed to permit greater inter-laboratory comparability.
Judy-Anne W. Chapman, Betty G. Mobbs, Wedad M. Hanna, Carol A. Sawka, Kathleen I. Pritchard, H.Lavina Lickley, Maureen E. Trudeau, Eamonn D. Ryan, Teik C. Ooi, Donald J.A. Sutherland, Eugene R. Tustanoff, David R. McCready   +11 more
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The estrogen receptor family

Current Opinion in Obstetrics and Gynaecology, 1999
A significant flow of new data is currently being generated within the field of estrogen receptors and their mechanisms of action. This is primarily a result of the development of estrogen receptor knockout mice and the discovery of the second estrogen receptor, estrogen receptor beta.
M, Warner, S, Nilsson, J A, Gustafsson
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An update on estrogen receptors

Seminars in Perinatology, 2000
The discovery of a second estrogen receptor (ER), ERbeta, has led to a complete change in our views on estrogen action. The previous dogmatic view that ERalpha represented the only estrogen receptor led to a static and simplistic concept of mechanisms of estrogen action with conceptual limitations in the development of novel estrogenic and ...
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Transcriptional Suppression of the Estrogen Receptor by Truncated Estrogen Receptor-Alpha

Hormone and Metabolic Research, 2002
The estrogen receptor (ER) is composed of six major functional domains - the A/B domain as the activation function 1 domain, domain C as the DNA-binding domain, domain D as a hinge domain, and domain E/F as the ligand-dependent transcriptional domains. A novel protein (designated as SRB-RGS) that interacted with domains C and D of ER alpha (ER alpha C ...
M, Ikeda, M, Okai, T, Miyoshi, S, Tone, Y, Minatogawa   +4 more
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ESTROGEN RECEPTORS IN RAT BONE: THEIR INTERACTION WITH ESTROGEN RECEPTOR MODULATORS

Endocrine Research, 2001
Estrogen receptors (ER) were studied in rat bone cytosol using immunoprecipitation, and Western blot technique. Ligand specificity of bone ER was studied using various known modulators of ER. Competitive experiments were performed under exchange conditions in bone tissue obtained from one day old rats.
R, Pal, R, Chaturvedi, K K, Kamboj, S R, Chowdhury, A, Dwivedi   +4 more
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Estrogen receptor α is essential for induction of oxytocin receptor by estrogen

NeuroReport, 1998
The induction of oxytocin receptor (OTR) synthesis in the periphery and in the brain by estrogen is critical for reproductive success. Oxytocin receptors are involved in the control of parturition, milk ejection, and sexual and maternal behaviors.
L J, Young, Z, Wang, R, Donaldson, E F, Rissman   +3 more
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The histochemistry of estrogen receptors

Histochemistry, 1981
Estrogen receptors in frozen section of the rat uterus were demonstrated by a radiolabeled ligand binding technique. The bound hormone was extracted with ethanol and measured by liquid scintillation. The binding of 3H-estradiol-17 beta at various molar concentrations was inhibited by a 100-fold excess of DES, and the bound 3H-estradiol resisted ...
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Estrogen dependent signaling in reproductive tissues – A role for estrogen receptors and estrogen related receptors

Molecular and Cellular Endocrinology, 2012
Estrogens play a fundamental role in the development and normal physiological function of multiple tissue systems and have been implicated in the ontogeny of cancers. The biological effects of estrogens are classically mediated via interaction with cognate nuclear receptors.
Douglas A, Gibson, Philippa T K, Saunders   +1 more
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Estrogen Receptors in Human Preadipocytes

Endocrine, 2001
Estrogen influences regional adipose tissue distribution and the accompanying cardiovascular disease risk. To elucidate the mechanisms of this link further, we assessed whether human preadipocytes (PAs) expressed estrogen receptors (ERs) and whether there were any regional or gender differences in ER complement. Human PAs expressed the ERalpha gene but
Joyner, J. M., Hutley, L. J., Cameron, D. P.   +2 more
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Estrogen Receptors

JAMA: The Journal of the American Medical Association, 1977
L E, Posey, L R, Morgan, R M, Beazley, J, Lanasa, J, Torres, E D, Krementz, R D, Carter, C, Sutherland, W, Hawley   +8 more
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