Results 241 to 250 of about 282,884 (313)

Exploring the Anticancer Activity of Ruthenium(II)–Arene and Copper(I) Complexes Bearing N‐Heterocyclic Carbene Ligands Containing Azido, Pyridinium, and Ethisterone‐Derived Triazole Groups

European Journal of Inorganic Chemistry, EarlyView.
A versatile library of backbone‐functionalized N‐heterocyclic carbene (NHC) ligands was developed and efficiently converted into Cu(I) and Ru(II) NHC complexes, demonstrating that ligand functionalization strongly modulates anticancer activity, with Cu(I)–NHC species showing potent and selective antiproliferative effects against ovarian and breast ...
Alessia Schiavo, Chiara Tupini, Nicola Demitri, Ilaria Lampronti, Thomas Scattolin   +4 more
wiley   +1 more source

Molecular Profiling and Treatment Outcomes in Uterine Serous Carcinoma: Prognostic Role of Estrogen Receptor Expression. [PDF]

Curr Oncol
Svarna A, Liontos M, Goula K, Pardali K, Koutsoumpogeras K, Aravantinou K, Perdikari KC, Kollarou I, Kaparelou M, Haidopoulos D, Dimitrakakis C, Dimopoulos MA, Zagouri F.   +12 more
europepmc   +1 more source

Additional file 2 of Panax quinquefolium saponin decreases atherosclerosis in ovariectomized ApoE−/− mice via regulating estrogen receptor α

Li Chen, Jun-He Shi, Xiaojuan Ma, Hua Chai, Kang-Kang Wei, Zhen Yang, Yu Tan, H Huang, Da-Zhuo Shi, Hua Qu   +9 more
openalex   +2 more sources

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source

Genetic regulation of the estrogen receptor and inherited predisposition to breast cancer. [PDF]

Proc Natl Acad Sci U S A
Pierce SB, Kortbawi H, Gulsuner S, Mandell JB, Lee MK, Walsh T, King MC.   +6 more
europepmc   +1 more source

Ambient technology in epilepsy clinical practice

Epilepsia Open, EarlyView.
Abstract The utilization of large language model‐based artificial intelligence (AI) in the field of neurology has gained attention as a viable tool to enhance and assist providers with processes ranging from scheduling patients to providing preliminary interpretations of testing results, pending orders, and documenting encounters. Epileptologists could
Haania Kakwan, Justin F. Rousseau, Lidia M. Moura, Irfan S. Sheikh   +3 more
wiley   +1 more source

An estrogen receptor/E2F1/CDKN3 axis protects from UV-induced skin cancers in females. [PDF]

EMBO Rep
Lukowicz C, Winkler C, Roger C, Fowler JC, Tsai YC, Meuli J, Claudinot S, Chang YT, Iselin C, Jones PH, Guenova E, Jafari P, Michalik L.   +12 more
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Protocol to Establish Estrogen Receptor-Negative Heterozygous BRCA1 Organoids. [PDF]

Methods Protoc
Deshpande M, Gerhardt J.
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source