Results 31 to 40 of about 475,258 (257)

The significance of GATA3 expression in breast cancer: a 10-year follow-up study. [PDF]

open access: yes, 2009
GATA3 is a transcription factor closely associated with estrogen receptor alpha in breast carcinoma, with a potential prognostic utility. This study investigated the immunohistochemical expression of GATA3 in estrogen receptor alpha-positive and estrogen
Ciocca, Robin M   +4 more
core   +2 more sources

A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]

open access: yes, 2018
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A.   +12 more
core   +4 more sources

Stratification of Estrogen Receptor-Negative Breast Cancer Patients by Integrating the Somatic Mutations and Transcriptomic Data

open access: yesFrontiers in Genetics, 2021
Patients with estrogen receptor-negative breast cancer generally have a worse prognosis than estrogen receptor-positive patients. Nevertheless, a significant proportion of the estrogen receptor-negative cases have favorable outcomes. Identifying patients
Jie Hou   +3 more
doaj   +1 more source

Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]

open access: yes, 1989
Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla   +36 more
core   +1 more source

The Effect of Estrogen Receptor Status on Survival in Breast Cancer Patients in Ethiopia. Retrospective Cohort Study

open access: yesBreast Cancer: Targets and Therapy, 2022
Abebe Muche Belete,1 Yared Asmare Aynalem,2 Belete Negese Gemeda,2 Tefera Mulugeta Demelew,3 Wondimeneh Shibabaw Shiferaw2 1Department of Biomedical Science, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Nursing, Debre Berhan University,
Belete AM   +4 more
doaj  

Estrogen and progesterone receptor expression in breast carcinoma

open access: yesJournal of Pathology of Nepal, 2011
Background: Breast carcinoma is the most common malignancy diagnosed among women worldwide and second leading cause of cancer mortality. One of the hallmarks of the disease is expression of estrogen receptor and progesterone receptor that ultimately ...
TB Pathak   +7 more
doaj   +1 more source

The importance of simultaneous determination of breast cancer biomarkers [PDF]

open access: yesArchive of Oncology, 2002
It is shown that steroid hormone receptors by themselves are not sufficiently strong prognostic factors in management of breast cancer. For that reason, simultaneous consideration of different biomarkers seems to be more appropriate for clinical use, i.e.
Markićević Milan   +3 more
doaj   +1 more source

Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]

open access: yes, 2010
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana   +9 more
core   +1 more source

UJI IN SILICO SENYAWA 2,6-DIHIDROKSIANTRAQUINON SEBAGAI LIGAN PADA RESEPTOR ESTROGEN ALFA

open access: yesJurnal Farmasi Sains dan Komunitas, 2015
Previous studies has shown that estrogen receptor alpha that binds to estrogen may increase cancer cell proliferation, thus estrogen receptor alpha can be targeted to cure breast cancer.
Felicia Fraulein Setiawan   +1 more
doaj   +1 more source

Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]

open access: yes, 2016
To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa   +7 more
core   +1 more source

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