Research progress of neurovascular units involved in ischemic stroke
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang+4 more
wiley +1 more source
Protein‐binding approaches for improving bioaccessibility and bioavailability of anthocyanins
Abstract Color is an important characteristic of food. Over the last 15 years, more attention has been paid to natural colorants because of the rising demand for clean‐label food products. Anthocyanins, which are a group of phytochemicals responsible for the purple, blue or red hues of many plants, offer a market advantage.
Haizhou Wu+2 more
wiley +1 more source
Expression of estrogen receptor-alpha and -beta mRNAs in the male reproductive system of the rat as revealed by in situ hybridization [PDF]
CN Mowa, Toshihiko Iwanaga
openalex +1 more source
Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection
Abstract COVID‐19 remains a life‐threatening infectious disease worldwide. Several bio‐active agents have been tested and evaluated in an effort to contain this disease. Unfortunately, none of the therapies have been successful, owing to their safety concerns and the presence of various adverse effects.
Sumel Ashique+13 more
wiley +1 more source
Androgen receptor (AR), estrogen receptor‐alpha (ER‐α) and estrogen receptor‐beta (ER‐β) expression in the testis of the newt, Triturus marmoratus marmoratus during the annual cycle [PDF]
M. Isabel Arenas+5 more
openalex +1 more source
The transcription factor RIP140 regulates interferon γ signaling in breast cancer
What's New? Interferon γ (IFNγ) is a key player in breast cancer, with the potential to induce apoptosis and to shift tumors into a dormant state. However, it also may promote carcinogenesis and angiogenesis. In this study, transcriptomic analysis identified the transcription factor RIP140 as a key regulator of IFNγ signaling in breast cancer.
Stéphan Jalaguier+9 more
wiley +1 more source
Obesity in female mice, when combined with estrogen deficiency, has a detrimental impact on bone quality, caused by expansion of bone marrow adiposity, upregulation of pro‐inflammatory markers, upregulation of senescence‐associated phenotype markers and accumulation of senescent cells.
Dalia Ali+10 more
wiley +1 more source
Estrogen response element binding induces alterations in estrogen receptor-alpha conformation as revealed by susceptibility to partial proteolysis [PDF]
TL Ramsey, Carolyn M. Klinge
openalex +1 more source
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder+2 more
wiley +1 more source
Astragaloside IV inhibits vascular calcification through estrogen receptor alpha. [PDF]
Nanao-Hamai M+3 more
europepmc +1 more source