Results 161 to 170 of about 121,912 (288)

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Protein‐binding approaches for improving bioaccessibility and bioavailability of anthocyanins

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 22, Issue 1, Page 333-354, January 2023., 2023
Abstract Color is an important characteristic of food. Over the last 15 years, more attention has been paid to natural colorants because of the rising demand for clean‐label food products. Anthocyanins, which are a group of phytochemicals responsible for the purple, blue or red hues of many plants, offer a market advantage.
Haizhou Wu   +2 more
wiley   +1 more source

Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection

open access: yesInternational Journal of Rheumatic Diseases, Volume 26, Issue 1, Page 13-30, January 2023., 2023
Abstract COVID‐19 remains a life‐threatening infectious disease worldwide. Several bio‐active agents have been tested and evaluated in an effort to contain this disease. Unfortunately, none of the therapies have been successful, owing to their safety concerns and the presence of various adverse effects.
Sumel Ashique   +13 more
wiley   +1 more source

The transcription factor RIP140 regulates interferon γ signaling in breast cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Interferon γ (IFNγ) is a key player in breast cancer, with the potential to induce apoptosis and to shift tumors into a dormant state. However, it also may promote carcinogenesis and angiogenesis. In this study, transcriptomic analysis identified the transcription factor RIP140 as a key regulator of IFNγ signaling in breast cancer.
Stéphan Jalaguier   +9 more
wiley   +1 more source

High‐fat diet‐induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice

open access: yesAging Cell, Volume 21, Issue 12, December 2022., 2022
Obesity in female mice, when combined with estrogen deficiency, has a detrimental impact on bone quality, caused by expansion of bone marrow adiposity, upregulation of pro‐inflammatory markers, upregulation of senescence‐associated phenotype markers and accumulation of senescent cells.
Dalia Ali   +10 more
wiley   +1 more source

The estrobolome: Estrogen‐metabolizing pathways of the gut microbiome and their relation to breast cancer

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder   +2 more
wiley   +1 more source

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